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Protein-coding gene in the species Homo sapiens
TBC1 domain family member 1 is a protein that in humans is encoded by the TBC1D1 gene .[ 5] [ 6]
TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and cell differentiation . These proteins share significant homology with TRE2 (USP6 ), yeast Bub2, and CDC16 (White et al., 2000).[supplied by OMIM][ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000065882 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029174 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ White RA, Pasztor LM, Richardson PM, Zon LI (Sep 2000). "The gene encoding TBC1D1 with homology to the tre-2/USP6 oncogene, BUB2, and cdc16 maps to mouse chromosome 5 and human chromosome 4". Cytogenet Cell Genet . 89 (3–4): 272–5. doi :10.1159/000015632 . PMID 10965142 . S2CID 22255963 . ^ a b "Entrez Gene: TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1" .
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