SUN domain-containing protein 5

SUN5
Identifiers
Aliases	SUN5, SPAG4L, TSARG4, dJ726C3.1, Sad1 and UNC84 domain containing 5, SPGF16
External IDs	OMIM: 613942; MGI: 1923657; HomoloGene: 12640; GeneCards: SUN5; OMA:SUN5 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	33,004,433 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	153,713,004 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; testicle; ; secondary oocyte; ; sperm; ; endothelial cell; ; external globus pallidus; ; synovial joint; ; jejunal mucosa; ; skin of hip;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; lumbar subsegment of spinal cord; ; lumbar spinal ganglion; ; temporal muscle; ; ear; ; gastrula; ; islet of Langerhans; ; carotid body;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein-membrane adaptor activity; molecular function;
Cellular component	integral component of membrane; membrane; nucleus; nuclear inner membrane; sperm connecting piece; Golgi apparatus; nuclear envelope; meiotic nuclear membrane microtubule tethering complex;
Biological process	nuclear envelope organization; spermatogenesis; cell differentiation; spermatid development;
	Sources:Amigo / QuickGO
Orthologs
	140732
	76407
	ENSG00000167098
	ENSMUSG00000027480
	Q8TC36
	Q9DA32
	NM_080675
	NM_029599; NM_001305048
	NP_542406
	NP_001291977; NP_083875
	Wikidata
View/Edit Human	View/Edit Mouse

SUN domain-containing protein 5, formerly known as sperm-associated antigen 4-like protein (SPAGL4), is a protein that in humans is encoded by the SUN5 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167098 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027480 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Tarnasky H, Gill D, Murthy S, Shao X, Demetrick DJ, van der Hoorn FA (Oct 1998). "A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2". Cytogenet Cell Genet. 81 (1): 65–7. doi:10.1159/000014990. hdl:1807.1/829. PMID 9691178. S2CID 30497041.
^ Shao X, Tarnasky HA, Lee JP, Oko R, van der Hoorn FA (Jul 1999). "Spag4, a novel sperm protein, binds outer dense-fiber protein Odf1 and localizes to microtubules of manchette and axoneme". Dev Biol. 211 (1): 109–23. doi:10.1006/dbio.1999.9297. PMID 10373309.
^ "Entrez Gene: SPAG4L sperm associated antigen 4-like".

Kierszenbaum AL, Tres LL (2003). "Bypassing natural sperm selection during fertilization: the azh mutant offspring experience and the alternative of spermiogenesis in vitro". Mol. Cell. Endocrinol. 187 (1–2): 133–8. doi:10.1016/S0303-7207(01)00692-X. PMID 11988320. S2CID 27072243.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Xing XW, Li LY, Fu JJ, et al. (2003). "[Cloning of cDNA of TSARG4, a human spermatogenesis related gene]". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao. 35 (3): 283–8. PMID 12621555.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167098 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027480 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9691178-5] Tarnasky H, Gill D, Murthy S, Shao X, Demetrick DJ, van der Hoorn FA (Oct 1998). "A novel testis-specific gene, SPAG4, whose product interacts specifically with outer dense fiber protein ODF27, maps to human chromosome 20q11.2". Cytogenet Cell Genet. 81 (1): 65–7. doi:10.1159/000014990. hdl:1807.1/829. PMID 9691178. S2CID 30497041.

[pmid10373309-6] Shao X, Tarnasky HA, Lee JP, Oko R, van der Hoorn FA (Jul 1999). "Spag4, a novel sperm protein, binds outer dense-fiber protein Odf1 and localizes to microtubules of manchette and axoneme". Dev Biol. 211 (1): 109–23. doi:10.1006/dbio.1999.9297. PMID 10373309.

[entrez-7] "Entrez Gene: SPAG4L sperm associated antigen 4-like".

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References

Further reading