60S ribosomal protein L24

RPL24
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X, 5A2Q, 5AJ0
Identifiers
Aliases	RPL24, HEL-S-310, L24, ribosomal protein L24
External IDs	OMIM: 604180; MGI: 1915443; HomoloGene: 763; GeneCards: RPL24; OMA:RPL24 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3q12.3 Start 101,681,091 bp End 101,686,718 bp
Gene location (Mouse) Chr. Chromosome 16 (mouse) Band 16 C1.1|16 33.74 cM Start 55,786,638 bp End 55,791,798 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon anterior pituitary ganglionic eminence left ovary islet of Langerhans thyroid gland corpus callosum left lobe of thyroid gland cerebellar hemisphere canal of the cervix Top expressed in embryo epiblast embryo morula ventricular zone urinary bladder ganglionic eminence uterus blastocyst thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding structural constituent of ribosome cadherin binding RNA binding Cellular component cytoplasm cytosol ribosome membrane cytosolic large ribosomal subunit extracellular exosome endoplasmic reticulum polysomal ribosome synapse Biological process assembly of large subunit precursor of preribosome viral transcription mitotic cell cycle checkpoint signaling exit from mitosis SRP-dependent cotranslational protein targeting to membrane retina development in camera-type eye ribosomal large subunit assembly translational initiation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay optic nerve development retinal ganglion cell axon guidance rRNA processing protein biosynthesis cytoplasmic translation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6152 68193 Ensembl ENSG00000114391 ENSMUSG00000098274 UniProt P83731 Q8BP67 RefSeq (mRNA) NM_000986 NM_024218 RefSeq (protein) NP_000977 NP_077180 Location (UCSC) Chr 3: 101.68 – 101.69 Mb Chr 16: 55.79 – 55.79 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

60S ribosomal protein L24 is a protein that in humans is encoded by the RPL24 gene.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24E family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as ribosomal protein L30 because the encoded protein shares amino acid identity with the L30 ribosomal proteins from Saccharomyces cerevisiae; however, its official name is ribosomal protein L24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Further reading

• Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol. 73 (11–12): 933–47. doi:10.1139/o95-101. PMID 8722009.
• Kato S, Sekine S, Oh SW, et al. (1995). "Construction of a human full-length cDNA bank". Gene. 150 (2): 243–50. doi:10.1016/0378-1119(94)90433-2. PMID 7821789.
• Cross SH, Charlton JA, Nan X, Bird AP (1994). "Purification of CpG islands using a methylated DNA binding column". Nat. Genet. 6 (3): 236–44. doi:10.1038/ng0394-236. PMID 8012384. S2CID 12847618.
• Johnson KR (1993). "Characterization of cDNA clones encoding the human homologue of Saccharomyces cerevisiae ribosomal protein L30". Gene. 123 (2): 283–5. doi:10.1016/0378-1119(93)90139-T. PMID 8428672.
• Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders". Genomics. 72 (3): 223–30. doi:10.1006/geno.2000.6470. PMID 11401437.
• Yoshihama M, Uechi T, Asakawa S, et al. (2002). "The Human Ribosomal Protein Genes: Sequencing and Comparative Analysis of 73 Genes". Genome Res. 12 (3): 379–90. doi:10.1101/gr.214202. PMC 155282. PMID 11875025.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Odintsova TI, Müller EC, Ivanov AV, et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". J. Protein Chem. 22 (3): 249–58. doi:10.1023/A:1025068419698. PMID 12962325. S2CID 10710245.
• Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
• Lehner B, Sanderson CM (2004). "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Tu LC, Yan X, Hood L, Lin B (2007). "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells". Mol. Cell. Proteomics. 6 (4): 575–88. doi:10.1074/mcp.M600249-MCP200. PMID 17220478.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.