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'''Posttraumatic stress disorder'''<ref name=DSM4>{{cite book |author= American Psychiatric Association|title=Diagnostic and statistical manual of mental disorders: DSM-IV |publisher=American Psychiatric Association |location=Washington, DC |year=1994 |pages= |isbn=0890420610 |oclc= |doi=}}; [http://www.behavenet.com/capsules/disorders/ptsd.htm on-line]</ref><ref name="Brunet"/> (commonly referred to by its acronym, '''PTSD''') is an [[anxiety disorder]] that can develop after exposure to one or more traumatic events that threatened or caused great physical harm.
'''Posttraumatic stress disorder'''<ref name=DSM4>{{cite book |author= American Psychiatric Association|title=Diagnostic and statistical manual of mental disorders: DSM-IV |publisher=American Psychiatric Association |location=Washington, DC |year=1994 |pages= |isbn=0890420610 |oclc= |doi=}}; [http://www.behavenet.com/capsules/disorders/ptsd.htm on-line]</ref><ref name="Brunet"/> (commonly referred to by its acronym, '''PTSD''') is an [[anxiety disorder]] that can develop after exposure to one or more traumatic events that threatened or caused great physical harm.


It is a severe and ongoing emotional reaction to an extreme [[psychological trauma]].<ref name="surgeon42">{{cite book | year=1999| chapter=Chapter 4.2 | author=[[David Satcher]] et al.| title=Mental Health: A Report of the Surgeon General| url=http://www.surgeongeneral.gov/library/mentalhealth/chapter4/sec2.html}}</ref> This stressor may involve the threat of death to oneself or to someone else, or any grave threat to one's own or someone else's physical, sexual, or psychological integrity,<ref name=DSM4/> overwhelming the individual's [[coping (psychology)|psychological defenses]].
It is a severe and ongoing emotional reaction to an extreme [[psychological trauma],LEK BEING LOCKED IN CUPBOARDS INNIT BRUV BRUV.<ref name="surgeon42">{{cite book | year=1999| chapter=Chapter 4.2 | author=[[David Satcher]] et al.| title=Mental Health: A Report of the Surgeon General| url=http://www.surgeongeneral.gov/library/mentalhealth/chapter4/sec2.html}}</ref> This stressor may involve the threat of death to oneself or to someone else, or any grave threat to one's own or someone else's physical, sexual, or psychological integrity,<ref name=DSM4/> overwhelming the individual's [[coping (psychology)|psychological defenses]].


PTSD is a more chronic and less frequent consequence of trauma than the normal [[acute stress reaction|acute stress response]].
PTSD is a more chronic and less frequent consequence of trauma than the normal [[acute stress reaction|acute stress response]].
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[[vi:Rối loạn stress sau sang chấn]]
[[vi:Rối loạn stress sau sang chấn]]
[[zh:创伤后心理压力紧张综合症]]
[[zh:创伤后心理压力紧张综合症]]
IM SORRY I BROKE EH PAGE,BUT LANNA LOVES JACK AND SAVANNAH

Revision as of 23:59, 12 November 2009

Post-traumatic stress disorder
SpecialtyPsychiatry, clinical psychology Edit this on Wikidata

Posttraumatic stress disorder[1][2] (commonly referred to by its acronym, PTSD) is an anxiety disorder that can develop after exposure to one or more traumatic events that threatened or caused great physical harm.

It is a severe and ongoing emotional reaction to an extreme [[psychological trauma],LEK BEING LOCKED IN CUPBOARDS INNIT BRUV BRUV.[3] This stressor may involve the threat of death to oneself or to someone else, or any grave threat to one's own or someone else's physical, sexual, or psychological integrity,[1] overwhelming the individual's psychological defenses.

PTSD is a more chronic and less frequent consequence of trauma than the normal acute stress response. PTSD has also been recognized in the past as railway spine, stress syndrome, shell shock, battle fatigue, traumatic war neurosis, or post-traumatic stress syndrome.

Diagnostic symptoms include re-experiencing original trauma(s), by means of flashbacks or nightmares; avoidance of stimuli associated with the trauma; and increased arousal, such as difficulty falling or staying asleep, anger, and hypervigilance. Formal diagnostic criteria (both DSM-IV and ICD-9) require that the symptoms last more than one month and cause significant impairment in social, occupational, or other important areas of functioning (e.g. problems with work and/or relationships).[1]

Causes

Psychological trauma

Main article: Psychological trauma

PTSD is believed to be caused by either physical trauma or psychological trauma, or more frequently a combination of both.[1] Possible sources of trauma include experiencing or witnessing childhood or adult physical, emotional or sexual abuse.[1] In addition, experiencing or witnessing an event perceived as life-threatening such as physical assault, adult experiences of sexual assault, accidents, drug addiction,[citation needed] illnesses, medical complications, or employment in occupations exposed to war (such as soldiers) or disaster (such as emergency service workers).

Traumatic events that may cause PTSD symptoms to develop include violent assault, kidnapping, sexual assault, torture, being a hostage, prisoner of war or concentration camp victim, experiencing a disaster, violent automobile accidents or getting a diagnosis of a life-threatening illness.[1] Children may develop PTSD symptoms by experiencing bullying[4] or sexually traumatic events like age-inappropriate sexual experiences.[1]

Witnessing traumatic experiences or learning about these experiences may also cause the development of PTSD symptoms.[1]

A preliminary study found that mutations in a stress-related gene interact with child abuse to increase the risk of PTSD in adults.[5][6][7]

Neuroendocrinology

PTSD displays biochemical changes in the brain and body that differ from other psychiatric disorders such as major depression. Individuals diagnosed with PTSD respond more strongly to a dexamethasone suppression test than individuals diagnosed with clinical depression.[8][9]

In addition, most people with PTSD also show a low secretion of cortisol and high secretion of catecholamines in urine, with a norepinephrine/cortisol ratio consequently higher than comparable non-diagnosed individuals.[10] This is in contrast to the normative fight-or-flight response, in which both catecholamine and cortisol levels are elevated after exposure to a stressor.[citation needed]

Brain catecholamine levels are low,[11] and corticotropin-releasing factor (CRF) concentrations are high.[12][13] Together, these findings suggest abnormality in the hypothalamic-pituitary-adrenal (HPA) axis.

Given the strong cortisol suppression to dexamethasone in PTSD, HPA axis abnormalities are likely predicated on strong negative feedback inhibition of cortisol, itself likely due to an increased sensitivity of glucocorticoid receptors.[14] Some researchers have associated the response to stress in PTSD with long-term exposure to high levels of norepinephrine and low levels of cortisol, a pattern associated with improved learning in animals.[citation needed]

Translating this reaction to human conditions gives a pathophysiological explanation for PTSD by a maladaptive learning pathway to fear response through a hypersensitive, hyperreactive and hyperresponsive HPA axis.[15]

Low cortisol levels may predispose individuals to PTSD: Following war trauma, Swedish soldiers serving in Bosnia and Herzegovina with low pre-service salivary cortisol levels had a higher risk of reacting with PTSD symptoms, following war trauma, than soldiers with normal pre-service levels.[16] Because cortisol is normally important in restoring homeostasis after the stress response, it is thought that trauma survivors with low cortisol experience a poorly contained—that is, longer and more distressing—response, setting the stage for PTSD.

However, there is considerable controversy within the medical community regarding the neurobiology of PTSD. A review of existing studies on this subject showed no clear relationship between cortisol levels and PTSD. Only a slight majority have found a decrease in cortisol levels while others have found no effect or even an increase.[17]

Neuroanatomy

Brain structures involved in dealing with stress and fear.[18]

In addition to biochemical changes, PTSD also involves changes in brain morphology. In a study by Gurvits et al., Combat veterans of the Vietnam war with PTSD showed a 20% reduction in the volume of their hippocampus compared with veterans who suffered no such symptoms.[19]

In human studies, the amygdala has been shown to be strongly involved in the formation of emotional memories, especially fear-related memories. Neuroimaging studies in humans have revealed both morphological and functional aspects of PTSD.

The amygdalocentric model of PTSD proposes that it is associated with hyperarousal of the amygdala and insufficient top-down control by the medial prefrontal cortex and the hippocampus. Further animal and clinical research into the amygdala and fear conditioning may suggest additional treatments for the condition.

Genetics

There is evidence that susceptibility to PTSD is hereditary. For twin pairs exposed to combat in Vietnam, having a monozygotic (identical) twin with PTSD was associated with an increased risk of the co-twin having PTSD compared to twins that were dizygotic (non-identical twins).[20]

Recently, it has been found that several single nucleotide polymorphisms (SNPs) in FK506 binding protein 5 (FKBP5) interact with childhood trauma to predict severity of adult PTSD.[21] These findings suggest that individuals with these SNPs who are abused as children are more susceptible to PTSD as adults.

This is particularly interesting given that FKBP5 SNPs have previously been associated with peritraumatic dissociation (that is, dissociation at the time of the trauma),[22] which has itself been shown to be predictive of PTSD.[23][24] Furthermore, FKBP5 may be less expressed in those with current PTSD.[25]

Risk and protective factors for PTSD development

See also: Psychological resilience

Although most people (50-90%) encounter trauma over a lifetime,[26][27] only about 8% develop full PTSD.[26] Vulnerability to PTSD presumably stems from an interaction of biological diathesis, early childhood developmental experiences, and trauma severity.

Predictor models have consistently found that childhood trauma, chronic adversity, and familial stressors increase risk for PTSD as well as risk for biological markers of risk for PTSD after a traumatic event in adulthood.[28][29][30][31] This effect of childhood trauma, which is not well understood, may be a marker for both traumatic experiences and attachment problems.[32][33]

Proximity to, duration of, and severity of the trauma also make an impact; and interpersonal traumas cause more problems than impersonal ones.[34]

Schnurr, Lunney, and Sengupta identified risk factors for the development of PTSD in Vietnam veterans. Among those are:

  • Hispanic ethnicity, coming from an unstable family, being punished severely during childhood, childhood asocial behavior and depression as pre-military factors
  • war-zone exposure, peritraumatic dissociation, depression as military factors
  • recent stressful life events, post-Vietnam trauma and depression as post-military factors

They also identified certain protective factors, such as:

  • Japanese-American ethnicity, high school degree or college education, older age at entry to war, higher socioeconomic status and a more positive paternal relationship as pre-military protective factors
  • Social support at homecoming and current social support as post-military factors.[35] Other research also indicates the protective effects of social support in averting and recovery from PTSD.[36][37]

There may also be an attitudinal component; for example, a soldier who believes that they will not sustain injuries may be more likely to develop symptoms of PTSD than one who anticipates the possibility, should either be wounded. Likewise, the later incidence of suicide among those injured in home fires above those injured in fires in the workplace suggests this possibility.

Diagnosis

The diagnostic criteria for PTSD, per the Diagnostic and Statistical Manual of Mental Disorders IV (Text Revision) (DSM-IV-TR), may be summarized as:[1]

A. Exposure to a traumatic event
B. Persistent reexperience (e.g. flashbacks, nightmares)
C. Persistent avoidance of stimuli associated with the trauma (e.g. avoidance of experiences that they fear will trigger flashbacks and reexperiencing of symptoms fear of losing control)
D. Persistent symptoms of increased arousal (e.g. difficulty falling or staying asleep, anger and hypervigilance)
E. Duration of symptoms for more than 1 month
F. Significant impairment in social, occupational, or other important areas of functioning (e.g. problems with work and relationships.)

Notably, criterion A2 requires that "the person’s response involved intense fear, helplessness, or horror." The DSM-IV-TR criterion differs substantially from the previous DSM-III-R stressor criterion, which specified the traumatic event should be of a type that would cause "significant symptoms of distress in almost anyone," and that the event was "outside the range of usual human experience."

Since the introduction of DSM-IV, the number of possible PTSD traumas has increased and one study suggests that the increase is around 50%.[38] Various scales exist to measure the severity and frequency of PTSD symptoms.[39][40]

Treatment

Early interventions

Some benefit has been found from early access to cognitive behavioral therapy, as well as from some medications such as propranolol. Effects of all these prevention strategies is modest.[41]

Critical incident stress management[42] (CISM) has been used to attempt to reduce effects of a potentially traumatic incident, and to attempt to prevent a full-blown occurrence of PTSD. However, recent studies regarding CISM seem to indicate iatrogenic effects.[43][44] Six studies[citation needed] have formally looked at the effect of CISM, four finding no benefit for preventing PTSD, and the other two studies indicating that CISM actually made things worse. Hence this is not a recommended treatment.

Psychotherapeutic interventions

Many forms of psychotherapy have been advocated for trauma-related problems such as PTSD. Basic counseling practices common to many treatment responses for PTSD include education about the condition and provision of safety and support.[45]

The psychotherapy programs with the strongest demonstrated efficacy include cognitive behavioral programs, variants of exposure therapy, stress inoculation training (SIT), variants of cognitive therapy (CT), eye movement desensitization and reprocessing (EMDR), and many combinations of these procedures.[46][47]

The British Journal of Psychiatry has recommended EMDR or trauma-specific cognitive behavioral therapy as first-line treatments for trauma victims.[48] A meta-analytic comparison of EMDR and cognitive behavioral therapy found both protocols indistinguishable in terms of effectiveness in treating PTSD.[49]

Cognitive behavioral therapy

Cognitive Behavioral Therapy (CBT) is a psychotherapeutic approach that aims to change the patterns of thinking and/or behavior that are responsible for a trauma victim’s negative emotions and, in doing so, change the way they feel and act. CBT has been proven to be an effective treatment for PTSD, and is currently considered the standard of care for PTSD by the Department of Defense[citation needed]. In CBT, individuals learn to identify thoughts that make them feel afraid or upset, and replace them with less distressing thoughts. The goal is to understand how certain thoughts about trauma cause stress and make symptoms worse.

Eye movement desensitization and reprocessing

Eye Movement Desensitization and Reprocessing (EMDR) is specifically targeted as a treatment for PTSD.[50] Based on the evidence of controlled research, the American Psychiatric Association[51] and the U.S. Department of Veterans Affairs and Department of Defense,[52] have placed EMDR in the highest category of effectiveness and research support in the treatment of trauma. Several international bodies have made similar recommendations.[53][54][55][56][57][58]

Exposure therapy

Exposure involves assisting trauma survivors to therapeutically confront distressing trauma-related memories and reminders in order to facilitate habituation and successful emotional processing of the trauma memory. Most exposure therapy programs include both imaginal confrontation with the traumatic memories and real-life exposure to trauma reminders.

Indeed, the success of exposure-based therapies has raised the question of whether exposure is a necessary ingredient in the treatment of PTSD. Some organizations have endorsed the need for exposure.[59][60]

Interpersonal psychotherapy

Other approaches, particularly involving social supports,[36][37] may also be important. An open trial of interpersonal psychotherapy[61] reported high rates of remission from PTSD symptoms without using exposure.[62] A current, NIMH-funded trial in New York City is now comparing interpersonal psychotherapy, prolonged exposure therapy, and relaxation therapy <http://www.columbiatrauma.org/>.

Medication

Medications have shown benefit in reducing PTSD symptoms, but "there is no clear drug treatment for PTSD". [63] Standard medication therapy useful in treating PTSD includes SSRIs (selective serotonin reuptake inhibitors) and TCAs (tricyclic antidepressants). Positive symptoms (re-experiencing, hypervigilance, increased arousal) generally respond better to medication than negative symptoms (avoidance, withdrawal).[63]

Tricyclics tend to be associated with greater side effects and lesser improvement of the three PTSD symptom clusters than SSRIs. SSRIs for which there are data to support use include: citalopram, escitalopram[64], fluvoxamine[65], paroxetine[66] and sertraline.[67]

There are data to support the use of "autonomic medicines" such as propranolol (beta blocker) and clonidine (alpha-adrenergic agonist) if there are significant symptoms of "over-arousal". These may inhibit the formation of traumatic memories by blocking adrenaline's effects on the amygdala, has been used in an attempt to reduce the impact of traumatic events,[68] or they may simply demonstrate to an individual that the symptoms can be controlled thereby assisting with "self efficacy" and helping the person remain calmer.

There are also data to support the use of mood-stabilizers such lithium carbonate and carbamazepine if there is significant uncontrolled mood or aggression.[69] Risperidone is used to help with dissociation, mood and aggression, and benzodiazepines are used for short-term anxiety relief.[70]

Recently the anticonvulsant lamotrigine has been reported to be useful in treating some people with PTSD.[71][72][73]

There is some evidence suggesting that administering glucocorticoids immediately after a traumatic experience may help prevent PTSD. Several studies have shown that individuals who receive high doses of hydrocortisone for treatment of septic shock or following surgery have a lower incidence and fewer symptoms of PTSD.[74][75][76] Additionally, post-stress high dose corticosterone administration was recently found to reduce 'PTSD-like' behaviors in a rat model of PTSD. In this study, corticosterone impaired memory performance, suggesting that it may reduce risk for PTSD by interfering with consolidation of traumatic memories.[77] The neurodegenerative effects of the glucocorticoids, however, may prove this treatment counterproductive.[78]

Combination therapies

PTSD is commonly treated using a combination of psychotherapy and medications.[citation needed]

Clinical trials evaluating methylenedioxymethamphetamine (MDMA, "Ecstasy") in conjunction with psychotherapy are being conducted in Switzerland[79] and Israel.[80] A clinical trial is also examining the efficacy of hydrocortisone in conjunction with exposure therapy for PTSD symptoms.[81]

Co-morbid substance dependence as an inhibitor of recovery

See also: Self-medication and Co-morbidity

Recovery from posttraumatic stress disorder or other anxiety disorders may be hindered, or the conditions worsened, by alcohol or benzodiazepine dependence. Treating co-morbid substance dependences particularly alcohol or benzodiazepine dependence can bring about a marked improvement in an individuals mental health status and anxiety levels. Recovery from benzodiazepines tends to take a lot longer than recovery from alcohol but people can regain their previous good health. Symptoms may temporarily worsen however, during alcohol withdrawal or benzodiazepine withdrawal.[82]

Epidemiology

Disability-adjusted life year rates for post-traumatic stress disorder per 100,000 inhabitants in 2002.[83]
  no data
  less than 10
  10-44.5
  44.5-45.5
  45.5-47
  47-48.5
  48.5-50
  50-51.5
  51.5-53
  53-54.5
  54.5-56
  56-57.5
  more than 57.5

There is debate over the rates of PTSD found in populations, but despite changes in diagnosis and the criteria used to define PTSD between 1997 and 2007, epidemiological rates have not changed significantly.[2]

United States

The National Comorbidity Survey has estimated that the lifetime prevalence of PTSD among adult Americans is 7.8%, with women (10.4%) twice as likely as men (5%) to have PTSD at some point in their lives.[26]

The United States Department of Veterans Affairs estimates that 830,000 Vietnam War veterans suffered symptoms of PTSD.[84] The National Vietnam Veterans' Readjustment Study (NVVRS) found 15.2% of male and 8.5% of female Vietnam Vets to suffer from current PTSD at the time of the study. Life-Time prevalence of PTSD was 30.9 for males and 26.9 for females. In a reanalysis of the NVVRS data, along with analysis of the data from the Matsunaga Vietnam Veterans Project, Schnurr, Lunney, Sengupta, and Waelde found that, contrary to the initial analysis of the NVVRS data, a large majority of Vietnam veterans suffered from PTSD symptoms (but not the disorder itself). Four out of five reported recent symptoms when interviewed 20–25 years after Vietnam.[35]

International PTSD rates

The United Nations' World Health Organization publishes estimates of PTSD impact for each of its member states; the latest data available are for 2004. Considering only the 25 most populated countries[85], Asian/Pacific countries have the highest estimated rates while those with the lowest rates are found in Africa, Europe, and the Americas. [86]


Disability-adjusted life year rates for PTSD, per 100,000 inhabitants, in 25 most populous countries[85], ranked by rate (2004)
Region Country PTSD DALY rate[86]
Asia / Pacific Iran 63
Asia / Pacific Thailand 62
Asia / Pacific Indonesia 61
Asia / Pacific Myanmar 60
Europe Turkey 59
Asia / Pacific Viet Nam 59
Asia / Pacific Bangladesh 57
Africa Egypt 57
Asia / Pacific Philippines 57
Asia / Pacific India 56
Asia / Pacific Russian Federation 56
Americas USA 56
Asia / Pacific China 55
Asia / Pacific Pakistan 55
Africa South Africa 54
Europe France 50
Asia / Pacific Japan 50
Europe United Kingdom 50
Europe Italy 49
Europe Germany 48
Americas Brazil 47
Africa Ethiopia 47
Africa Nigeria 47
Africa Dem. Republ. of Congo 46
Americas Mexico 46

History

Earliest reports

Reports of battle-associated stress appear as early as the 6th century BCE.[87] One of the first descriptions of PTSD was made by the Greek historian Herodotus. In 490 BCE he described, during the Battle of Marathon, an Athenian soldier who suffered no injury from war but became permanently blind after witnessing the death of a fellow soldier.[88]

In the early 1800's military medical doctors started diagnosing soldiers with "exhaustion" after the stress of battle. This "exhaustion" was characterized by mental shutdown due to individual or group trauma. Similar to present time, soldiers during the 1800's were not supposed to be scared or show any fear in the midst of battle. The only treatment for this "exhaustion" was to bring the afflicted to the back for a bit then send them back into battle. During the intense and frequently repeated stress, the soldiers became fatigued as a part of their body's natural shock reaction. [89]

One-tenth of mobilised American men were hospitalised for mental disturbances between 1942 and 1945, and after thirty-five days of uninterrupted combat, 98% of them manifested psychiatric disturbances in varying degrees.[90]

Although PTSD-like symptoms have also been recognized in combat veterans of many military conflicts since, the modern understanding of PTSD dates from the 1970s, largely as a result of the problems that were still being experienced by US military veterans of the war in Vietnam.[87]

Terminology

The term post-traumatic stress disorder or PTSD was coined in the mid 1970s.[87] Early in 1978, the term was used in a working group finding presented to the Committee of Reactive Disorders.[91] The term was formally recognized in 1980.[87] (In the authoritative DSM-IV, the spelling "posttraumatic stress disorder" is used. Elsewhere, "posttraumatic" is often rendered as two words — "post-traumatic stress disorder" or "post traumatic stress disorder" — especially in less formal writing on the subject.)

International/National public health response

In recent history, catastrophes (by human means or not) such as the Indian Ocean Tsunami Disaster may have caused PTSD in many survivors and rescue workers. Today relief workers from organizations such as the Red Cross and the Salvation Army provide counseling after major disasters as part of their standard procedures to curb severe cases of post-traumatic stress disorder.

In the United States

In part through the efforts of anti Vietnam war activists and the anti war group Vietnam Veterans Against the War and Chaim F. Shatan, who worked with them and coined the term post-Vietnam Syndrome, the condition was added to the DSM-III as posttraumatic stress disorder.[91]

A review of the provision of compensation to veterans for PTSD by the United States Department of Veterans Affairs began in 2005 after the VA had noted a 30% increase in PTSD claims in recent years. This led to a backlash from veterans'-rights groups, and to some highly-publicized suicides by veterans who feared losing their benefits,[citation needed] which in some cases constituted their only income. In response, on November 10, 2005, the Secretary of Veterans Affairs announced that "the Department of Veterans Affairs (VA) will not review the files of 72,000 veterans currently receiving disability compensation for post-traumatic stress disorder..."[92]

The diagnosis of PTSD has been a subject of some controversy due to uncertainties in objectively diagnosing PTSD in those who may have been exposed to trauma, and due to this diagnosis' association with some incidence of compensation-seeking behavior.[93]

Many veterans of the wars in Iraq and Afghanistan returning home have faced significant physical, emotional and relational disruptions. In response the United States Marine Corps has instituted programs to assist them in re-adjusting to civilian life - especially in their relationships with spouses and loved ones - to help them communicate better and understand what the other has gone through.[94] Similarly, Walter Reed Army Institute of Research (WRAIR) developed the Battlemind program to assist service members avoid or ameliorate PTSD and related problems. In the UK there has been some controversy that National Health Service is dumping veterans on service charities like Combat Stress.[95][96][97]

Canadian veterans

Veterans Affairs Canada offers a new program that includes rehabilitation, financial benefits, job placement, health benefits program, disability awards and family support.[98]

Society and culture

In recent decades, with the concept of trauma and PTSD in particular becoming just as much a cultural phenomenon as a medical or legal one[citation needed], artists have engaged the issue in their work. Many movies, such as the Bourne films, First Blood, Birdy, Born on the Fourth of July, Brothers, Coming Home, The Deer Hunter, Heaven & Earth, In the Valley of Elah, The War at Home, and Gran Torino deal with PTSD. It is an especially popular subject amongst "war veteran" films, often portraying Vietnam war veterans suffering from extreme PTSD and having difficulties adjusting to civilian life[citation needed]. Military-themed videogames have also begun touching on the subject; Metal Gear Solid 4: Guns of the Patriots presents the idea of a quick-fix technology that stops soldiers from experiencing an emotional reaction to combat, thus negating PTSD, and the ensuing trauma soldiers under this system suddenly find themselves with when the technology fails and leaves them without any built-up tolerance. Several characters in the game are revealed to have experienced extreme trauma at a young age, and PTSD over these events influences them into their adult lives[citation needed].

In more recent work, an example[citation needed] is that of Krzysztof Wodiczko who teaches at MIT and who is known for interviewing people and then projecting these interviews onto large public buildings.[99] Wodiczko aims to bring trauma not merely into public discourse but to have it contest the presumed stability of cherished urban monuments[citation needed]. His work has brought to life issues such as homelessness, rape, and violence[citation needed]. Other artists who engage the issue of trauma are Everlyn Nicodemus of Tanzania and Milica Tomic of Serbia.[100]

General Romeo Dallaire mentions his PTSD in his book, Shake hands with the Devil, which was adapted into a film.

Targets: Reporters in Iraq is a film made by Maziar Bahari that deals with journalists suffering PTSD in Iraq.

Posttraumatic stress disorder is the central subject of the Israeli film Waltz with Bashir, in which a former soldier struggles to cope with his traumatic memories of the 1982 Lebanon War twenty years later. The narrative of the film itself becomes structured entirely around the nature of PTSD recollection. In one scene, a specialist on post-traumatic stress disorder directly addresses his trauma.[101]

See also

References

  1. ^ a b c d e f g h i American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders: DSM-IV. Washington, DC: American Psychiatric Association. ISBN 0890420610.; on-line Cite error: The named reference "DSM4" was defined multiple times with different content (see the help page).
  2. ^ a b Brunet A, Akerib V, Birmes P (2007). "Don't throw out the baby with the bathwater (PTSD is not overdiagnosed)" (PDF). Can J Psychiatry. 52 (8): 501–2, discussion 503. PMID 17955912. Retrieved 2008-03-12.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ David Satcher; et al. (1999). "Chapter 4.2". Mental Health: A Report of the Surgeon General. {{cite book}}: Explicit use of et al. in: |author= (help)
  4. ^ Kelleher, I. (2008). "Associations between childhood trauma, bullying and psychotic symptoms among a school-based adolescent sample". Br J Psychiatry. 193 (5): 378–82. PMID 18978317. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)
  5. ^ Binder, MD. PhD, E. B. (2008). "Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults". JAMA. 299 (11): 1291–1305. doi:10.1001/jama.299.11.1291. PMID 18349090. Retrieved 2008-03-31. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help); Unknown parameter |month= ignored (help)
  6. ^ Template:Cite article
  7. ^ Template:Cite article
  8. ^ Yehuda R, Halligan SL, Golier JA, Grossman R, Bierer LM (2004). "Effects of trauma exposure on the cortisol response to dexamethasone administration in PTSD and major depressive disorder". Psychoneuroendocrinology. 29 (3): 389–404. PMID 14644068.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  9. ^ Yehuda R, Halligan SL, Grossman R, Golier JA, Wong C (2002). "The cortisol and glucocorticoid receptor response to low dose dexamethasone administration in aging combat veterans and holocaust survivors with and without posttraumatic stress disorder". Biol Psychiatry. 52 (5): 393–403. PMID 12242055.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  10. ^ Mason JW, Giller EL, Kosten TR, Harkness L (1988). "Elevation of urinary norepinephrine/cortisol ratio in posttraumatic stress disorder". J Nerv Ment Dis. 176 (8): 498–502. doi:10.1097/00005053-198808000-00008. PMID 3404142.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  11. ^ Geracioti TD Jr, Baker DG, Ekhator NN, West SA, Hill KK, Bruce AB, Schmidt D, Rounds-Kugler B, Yehuda R, Keck PE Jr, Kasckow JW (2001). "CSF norepinephrine concentrations in posttraumatic stress disorder". Am J Psychiatry. 158 (8): 1227–1230. PMID 11481155.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  12. ^ Sautter FJ, Bisette G, Wiley J, Manguno-Mire G, Schoenbachler B, Myers L, Johnson JE, Cerbone A, Malaspina D (2003). "Corticotropin-releasing factor in posttraumatic stress disorder with secondary psychotic symptoms, nonpsychotic PTSD, and healthy control subjects". Biol Psychiatry. 54 (12): 1382–8. doi:10.1016/S0006-3223(03)00571-7. PMID 14675802.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  13. ^ de Kloet CS, Vermetten E, Geuze E, Lentjes EG, Heijnen CJ, Stalla GK, Westenberg HG (2008). "Elevated plasma corticotrophin-releasing hormone levels in veterans with posttraumatic stress disorder". Prog Brain Res. 167: 287–91. PMID 18037027.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  14. ^ Yehuda R (2001). "Biology of posttraumatic stress disorder". J Clin Psychiatry. 62 Suppl 17: 41–6. PMID 11495096.
  15. ^ Yehuda R (2002). "Clinical relevance of biologic findings in PTSD". Psychiatr Q. 73 (2): 123–33. doi:10.1023/A:1015055711424. PMID 12025720.
  16. ^ Aardal-Eriksson E, Eriksson TE, Thorell LH (2001). "Salivary cortisol, posttraumatic stress symptoms, and general health in the acute phase and during 9-month follow-up". Biol. Psychiatry. 50 (12): 986–93. doi:10.1016/S0006-3223(01)01253-7. PMID 11750895.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  17. ^ Lindley SE, Carlson EB, Benoit M (2004). "Basal and dexamethasone suppressed salivary cortisol concentrations in a community sample of patients with posttraumatic stress disorder". Biol. Psychiatry. 55 (9): 940–5. doi:10.1016/j.biopsych.2003.12.021. PMID 15110738.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  18. ^ "NIMH · Post Traumatic Stress Disorder Research Fact Sheet". National Institutes of Health.
  19. ^ Carlson, Neil R. (2007). Physiology of Behavior (9 ed.). Pearson Education, Inc.
  20. ^ True WR, Rice J, Eisen SA; et al. (1993). "A twin study of genetic and environmental contributions to liability for posttraumatic stress symptoms". Arch. Gen. Psychiatry. 50 (4): 257–64. PMID 8466386. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  21. ^ Binder EB, Bradley RG, Liu W; et al. (2008). "Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults". JAMA. 299 (11): 1291–305. doi:10.1001/jama.299.11.1291. PMID 18349090. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  22. ^ Koenen KC, Saxe G, Purcell S; et al. (2005). "Polymorphisms in FKBP5 are associated with peritraumatic dissociation in medically injured children". Mol Psychiatry. 10 (12): 1058–9. doi:10.1038/sj.mp.4001727. PMID 16088328. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  23. ^ Birmes P, Brunet A, Carreras D; et al. (2003). "The predictive power of peritraumatic dissociation and acute stress symptoms for posttraumatic stress symptoms: a three-month prospective study". Am J Psychiatry. 160 (7): 1337–9. doi:10.1176/appi.ajp.160.7.1337. PMID 12832251. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  24. ^ Schnurr PP, Lunney CA, Sengupta A (2004). "Risk factors for the development versus maintenance of posttraumatic stress disorder". J Trauma Stress. 17 (2): 85–95. doi:10.1023/B:JOTS.0000022614.21794.f4. PMID 15141781.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  25. ^ Yehuda R, Cai G, Golier JA, Sarapas C, Galea S, Ising M, Rein T, Schmeidler J, Müller-Myhsok B, Holsboer F, Buxbaum JD (2009). "Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks". Biol Psychiatry: 2009 Apr 24 [Epub ahead of print]. PMID 19393990.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  26. ^ a b c Kessler RC, Sonnega A, Bromet E, Hughes M, Nelson CB (1995). "Posttraumatic stress disorder in the National Comorbidity Survey". Arch Gen Psychiatry. 52 (12): 1048–60. PMID 7492257. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  27. ^ Breslau N, Kessler RC, Chilcoat HD, Schultz LR, Davis GC, Andreski P (1998). "Trauma and posttraumatic stress disorder in the community: the 1996 Detroit Area Survey of Trauma". Arch Gen Psychiatry. 55 (7): 626–32. doi:10.1001/archpsyc.55.7.626. PMID 9672053. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  28. ^ Koenen KC, Moffitt TE, Poulton R, Martin J, Caspi A (2007). "Early childhood factors associated with the development of post-traumatic stress disorder: results from a longitudinal birth cohort". Psychol Med. 37 (2): 181–92. doi:10.1017/S0033291706009019. PMC 2254221. PMID 17052377. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  29. ^ Lapp KG, Bosworth HB, Strauss JL; et al. (2005). "Lifetime sexual and physical victimization among male veterans with combat-related post-traumatic stress disorder". Mil Med. 170 (9): 787–90. PMID 16261985. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  30. ^ Otte C, Neylan TC, Pole N; et al. (2005). "Association between childhood trauma and catecholamine response to psychological stress in police academy recruits". Biol. Psychiatry. 57 (1): 27–32. doi:10.1016/j.biopsych.2004.10.009. PMID 15607297. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  31. ^ Resnick HS, Yehuda R, Pitman RK, Foy DW (1995). "Effect of previous trauma on acute plasma cortisol level following rape". Am J Psychiatry. 152 (11): 1675–7. PMID 7485635. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  32. ^ Laor N, Wolmer L, Mayes LC; et al. (1996). "Israeli preschoolers under Scud missile attacks. A developmental perspective on risk-modifying factors". Arch Gen Psychiatry. 53 (5): 416–23. PMID 8624185. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  33. ^ Laor N, Wolmer L, Mayes LC, Gershon A, Weizman R, Cohen DJ (1997). "Israeli preschool children under Scuds: a 30-month follow-up". J Am Acad Child Adolesc Psychiatry. 36 (3): 349–56. doi:10.1097/00004583-199703000-00013. PMID 9055515. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  34. ^ Janoff-Bulman R: Shattered Assumptions: Toward a New Psychology of Trauma. New York: Free Press, 1992.
  35. ^ a b Jennifer L. Price, Ph.D.: Findings from the National Vietnam Veterans' Readjustment Study - Factsheet. National Center for PTSD. United States Department of Veterans Affairs [1].
  36. ^ a b Brewin CR, Andrews B, Valentine JD (2000). "Meta-analysis of risk factors for posttraumatic stress disorder in trauma-exposed adults". J Consult Clin Psychol. 68 (5): 748–66. doi:10.1037/0022-006X.68.5.748. PMID 11068961. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  37. ^ a b Ozer EJ, Best SR, Lipsey TL, Weiss DS (2003). "Predictors of posttraumatic stress disorder and symptoms in adults: a meta-analysis". Psychol Bull. 129 (1): 52–73. doi:10.1037/0033-2909.129.1.52. PMID 12555794. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  38. ^ Breslau N, Kessler RC (2001). "The stressor criterion in DSM-IV posttraumatic stress disorder: an empirical investigation". Biol. Psychiatry. 50 (9): 699–704. doi:10.1016/S0006-3223(01)01167-2. PMID 11704077.
  39. ^ Blake DD, Weathers FW, Nagy LM; et al. (1995). "The development of a Clinician-Administered PTSD Scale". J Trauma Stress. 8 (1): 75–90. PMID 7712061. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  40. ^ Foa E: The Post Traumatic Diagnostic Scale Manual. Minneapolis, NCS, 1995.
  41. ^ Feldner MT, Monson CM, Friedman MJ (2007). "A critical analysis of approaches to targeted PTSD prevention: current status and theoretically derived future directions". Behav Modif. 31 (1): 80–116. doi:10.1177/0145445506295057. PMID 17179532.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  42. ^ Brown, Asa Don Ph.D., "The effects of childhood trauma on adult perception and worldview", Capella University, 2008, 152 pages; AAT 3297512.
  43. ^ Carlier, IVE (1998). "Disaster-related post-traumatic stress in police officers: A field study of the impact of debriefing". Stress Medicine. 14 (3): 143–8. doi:10.1002/(SICI)1099-1700(199807)14:3<143::AID-SMI770>3.0.CO;2-S. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  44. ^ Mayou RA, Ehlers A, Hobbs M (2000). "Psychological debriefing for road traffic accident victims. Three-year follow-up of a randomised controlled trial". Br J Psychiatry. 176: 589–93. doi:10.1192/bjp.176.6.589. PMID 10974967.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  45. ^ Foa 1997.
  46. ^ Cahill, S. P., & Foa, E. B. (2004). A glass half empty or half full? Where we are and directions for future research in the treatment of PTSD. In S. Taylor (ed.), Advances in the Treatment of Posttraumatic Stress Disorder: Cognitive-behavioral perspectives (pp. 267-313) New York: Springer.
  47. ^ Brom D, Kleber RJ, Defares PB (1989). "Brief psychotherapy for posttraumatic stress disorders". J Consult Clin Psychol. 57 (5): 607–12. doi:10.1037/0022-006X.57.5.607. PMID 2571625. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  48. ^ Bisson JI, Ehlers A, Matthews R, Pilling S, Richards D, Turner S (2007). "Psychological treatments for chronic post-traumatic stress disorder. Systematic review and meta-analysis". The British Journal of Psychiatry : the journal of mental science. 190: 97–104. doi:10.1192/bjp.bp.106.021402. PMID 17267924.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  49. ^ Seidler GH, Wagner FE (2006). "Comparing the efficacy of EMDR and trauma-focused cognitive-behavioral therapy in the treatment of PTSD: a meta-analytic study". Psychol Med. 36 (11): 1515–22. doi:10.1017/S0033291706007963. PMID 16740177.
  50. ^ Devilly GJ, Spence SH (1999). "The relative efficacy and treatment distress of EMDR and a cognitive-behavior trauma treatment protocol in the amelioration of posttraumatic stress disorder". J Anxiety Disord. 13 (1–2): 131–57. doi:10.1016/S0887-6185(98)00044-9. PMID 10225505.
  51. ^ American Psychiatric Association (2004). "Practice Guideline for the treatment of patients with acute stress disorder and posttraumatic stress disorder". Arlington, VA: American Psychiatric Association Practice Guidelines. {{cite journal}}: Cite journal requires |journal= (help)
  52. ^ Department of Veteran Affairs & Department of Defense (2004), VA/DoD clinical practice guideline for the management of post-traumatic stress ([dead link‍] – Scholar search), Washington, DC: Author {{citation}}: External link in |format= (help)
  53. ^ Australian Centre for Posttraumatic Mental Health. (2007), Australian guidelines for the treatment of adults with acute stress disorder and post traumatic stress disorder, Melbourne, Victoria: ACPTMH. {{citation}}: Cite has empty unknown parameter: |unused_data= (help); Unknown parameter |isbn online= ignored (help)
  54. ^ National Institute for Clinical Excellence (2005), Post traumatic stress disorder (PTSD): The management of adults and children in primary and secondary care, London: NICE Guidelines
  55. ^ Dutch National Steering Committee Guidelines Mental Health and Care., Guidelines for the diagnosis treatment and management of adult clients with an anxiety disorder, Utrecht, Netherlands: The Dutch Institute for Healthcare Improvement (CBO)
  56. ^ Foa, E.B.; Keane, T.M.; Friedman, M.J. (2000), Effective treatments for PTST: Practice guidelines of the International Society for Traumatic Stress Studies, New York: Guilford Press
  57. ^ Bleich, A.; Kolter, M.; Kutz, E.; Shaley, A. (2002), A position paper of the (Israeli) National Council for Mental Health: Guidelines for the assessment and professional intervention with terror victime in the hospital and the community, Jerusalem, Israel.{{citation}}: CS1 maint: location missing publisher (link)
  58. ^ United Kingdom Department of Health (2001), Treatment choice in psychological therapies and counseling evidence based on clinical practice guideline, London: Author
  59. ^ Ursano RJ, Bell C, Eth S; et al. (2004). "Practice guideline for the treatment of patients with acute stress disorder and posttraumatic stress disorder". Am J Psychiatry. 161 (11 Suppl): 3–31. doi:10.1176/appi.ajp.161.1.3. PMID 15617511. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  60. ^ Committee on Treatment of Posttraumatic Stress Disorder, Institute of Medicine: Treatment of Posttraumatic Stress Disorder: An Assessment of the Evidence. Washington, D.C.: National Academies Press, 2008 ISBN 0-309-10926-4.
  61. ^ Weissman MM, Markowitz JC, Klerman GL: Clinician’s Quick Guide to Interpersonal Psychotherapy. New York: Oxford University Press, 2007.
  62. ^ Bleiberg KL, Markowitz JC (2005). "A pilot study of interpersonal psychotherapy for posttraumatic stress disorder". Am J Psychiatry. 162 (1): 181–3. doi:10.1176/appi.ajp.162.1.181. PMID 15625219. {{cite journal}}: Unknown parameter |month= ignored (help)
  63. ^ a b Maxmen, J. S.; Ward, N. G. (2002). Psychotropic drugs: fast facts (third ed.). New York: W. W. Norton. ISBN 0-393-70301-0.
  64. ^ Yehuda R (2000). "Biology of posttraumatic stress disorder". J Clin Psychiatry. 61 (Suppl 7): 14–21. PMID 10795605.
  65. ^ Marshall RD, Beebe KL, Oldham M, Zaninelli R (2001). "Efficacy and safety of paroxetine treatment for chronic PTSD: a fixed-dose, placebo-controlled study". Am J Psychiatry. 158 (12): 1982–8. doi:10.1176/appi.ajp.158.12.1982. PMID 11729013. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  66. ^ Brady K, Pearlstein T, Asnis GM; et al. (2000). "Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial". JAMA. 283 (14): 1837–44. doi:10.1001/jama.283.14.1837. PMID 10770145. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  67. ^ Davidson JR, Rothbaum BO, van der Kolk BA, Sikes CR, Farfel GM (2001). "Multicenter, double-blind comparison of sertraline and placebo in the treatment of posttraumatic stress disorder". Arch Gen Psychiatry. 58 (5): 485–92. doi:10.1001/archpsyc.58.5.485. PMID 11343529. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  68. ^ Pitman RK, Sanders KM, Zusman RM; et al. (2002). "Pilot study of secondary prevention of posttraumatic stress disorder with propranolol". Biol. Psychiatry. 51 (2): 189–92. doi:10.1016/S0006-3223(01)01279-3. PMID 11822998. {{cite journal}}: Explicit use of et al. in: |author= (help)CS1 maint: multiple names: authors list (link)
  69. ^ Lacy CF, Armstrong LL; et al. (2008). Drug Information Handbook. Lexi-Comp. {{cite book}}: Explicit use of et al. in: |author= (help); Text "pages 260, 934" ignored (help)
  70. ^ Reist C (2005) Post-traumatic Stress Disorder. Compendia, Build ID: F000005, published by Epocrates.com.
  71. ^ "Lamotrigine FAQ". Retrieved 2007-05-01.
  72. ^ SSRIs versus Non-SSRIs in Post-traumatic Stress Disorder, Department of Psychiatry and Behavioral Sciences, Montefiore Medical Center, Albert Einstein College of Medicine.
  73. ^ Hertzberg MA, Butterfield MI, Feldman ME; et al. (1999). "A preliminary study of lamotrigine for the treatment of posttraumatic stress disorder". Biol. Psychiatry. 45 (9): 1226–9. doi:10.1016/S0006-3223(99)00011-6. PMID 10331117. {{cite journal}}: Explicit use of et al. in: |author= (help); Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
  74. ^ Schelling G, Roozendaal B, Krauseneck T, Schmoelz M, DE Quervain D, Briegel J. (2006). "Efficacy of hydrocortisone in preventing posttraumatic stress disorder following critical illness and major surgery". Ann N Y Acad Sci. 1071: 46–53. PMID 16891561.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  75. ^ Weis F, Kilger E, Roozendaal B, de Quervain DJ, Lamm P, Schmidt M, Schmölz M, Briegel J, Schelling G. (2006). "Stress doses of hydrocortisone reduce chronic stress symptoms and improve health-related quality of life in high-risk patients after cardiac surgery: a randomized study". J Thorac Cardiovasc Surg. 131 (2): 277–282. PMID 16434254.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  76. ^ Schelling G, Kilger E, Roozendaal B, de Quervain DJ, Briegel J, Dagge A, Rothenhäusler HB, Krauseneck T, Nollert G, Kapfhammer HP. (2004). "Stress doses of hydrocortisone, traumatic memories, and symptoms of posttraumatic stress disorder in patients after cardiac surgery: a randomized study". Biol Psychiatry. 55 (6): 627–633. PMID 15013832.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  77. ^ Cohen H, Matar MA, Buskila D, Kaplan Z, Zohar J. (2008). "Early post-stressor intervention with high-dose corticosterone attenuates posttraumatic stress response in an animal model of posttraumatic stress disorder". Biol Psychiatry. 64 (8): 708–717. PMID 18635156.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  78. ^ Sapolsky RM, Romero LM, Munck AU. (2000). "How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions". Endocr Review. 21 (1): 55–89. PMID 10696570.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  79. ^ "Study of 3,4-Methylenedioxymethamphetamine-Assisted Psychotherapy in People With Posttraumatic Stress Disorder". ClinicalTrials.gov. U.S. National Institutes of Health. 2009. {{cite web}}: Unknown parameter |month= ignored (help) Retrieved on June 17, 2009.
  80. ^ "Randomized Placebo-Controlled Study of MDMA-Assisted Psychotherapy in People With PTSD - Israel". ClinicalTrials.gov. U.S. National Institutes of Health. 2009. {{cite web}}: Unknown parameter |month= ignored (help) Retrieved on June 17, 2009.
  81. ^ "Cortisol Augmentation of Prolonged Exposure Therapy". ClinicalTrials.gov. U.S. National Institutes of Health. 2009. {{cite web}}: Unknown parameter |month= ignored (help) Retrieved on June 17, 2009.
  82. ^ Cohen SI (1995). "Alcohol and benzodiazepines generate anxiety, panic and phobias". J R Soc Med. 88 (2): 73–7. PMC 1295099. PMID 7769598. {{cite journal}}: Unknown parameter |month= ignored (help)
  83. ^ "Mortality and Burden of Disease Estimates for WHO Member States in 2002" (xls). World Health Organization. 2002.
  84. ^ The War's Costs . Digital History.
  85. ^ a b List of countries by population
  86. ^ a b "Mortality and Burden of Disease Estimates for WHO Member States: Persons, all ages (2004)" (xls). World Health Organization. 2004. Retrieved 2009.11.12. {{cite web}}: Check date values in: |accessdate= (help)
  87. ^ a b c d When trauma tips you over: PTSD Part 1 All in the Mind, Australian Broadcasting Commission, 9 October 2004.
  88. ^ Swartz' Textbook of Physical Diagnosis: History and Examination.
  89. ^ [2]
  90. ^ World War One --- A New Kind of War | Part II, From 14 - 18 Understanding the Great War, by Stéphane Audoin-Rouzeau, Annette Becker
  91. ^ a b Shalev, Arieh Y.; Yehuda, Rachel; Alexander C. McFarlane (2000). International handbook of human response to trauma. New York: Kluwer Academic/Plenum Press. ISBN 0-306-46095-5.{{cite book}}: CS1 maint: multiple names: authors list (link); on-line.
  92. ^ United States Department of Veteran Affairs.
  93. ^ Vedantam, Shankar (2005-12-27). "A Political Debate On Stress Disorder: As Claims Rise, VA Takes Stock". Washington Post. Retrieved 2008-03-12.
  94. ^ ""Marine Corps Offers Yoga, Massages to Marriages Strained by War"". Associated Press. 2008-04-02. Retrieved 2008-04-03.
  95. ^ "Lance Corporal Johnson Beharry accuses Government of neglecting soldiers". Times Online. February 28, 2009. Retrieved 2009-08-29.
  96. ^ "British troops in Afghanistan face mental health timebomb 'on the scale of Vietnam' | Mail Online". Dailymail.co.uk. Retrieved 2009-08-29.
  97. ^ "UK | Full interview: L/Cpl Johnson Beharry". BBC News. 2009-02-28. Retrieved 2009-08-29.
  98. ^ "Vac-Acc.Gc.Ca". Vac-Acc.Gc.Ca. 2006-07-12. Retrieved 2009-08-29.
  99. ^ Mark Jarzombek (2006). "The Post-traumatic Turn and the Art of Walid Ra'ad and Krzysztof Wodiczko: from Theory to Trope and Beyond". In Rosenberg E, Saltzman L (ed.). Trauma and Visuality in Modernity (Interfaces: Studies in Visual Culture). Dartmouth College Press. ISBN 1-58465-516-X.
  100. ^ Elizabeth Cowie, "Perceiving Memory and Tales of the Other: the work of Milica Tomic," Camera Austria, no. [?], pp. 14-16.
  101. ^ “Waltz with Bashir” Two-Step Hillel Halkin. Commentary Magazine. March 2009 
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