PAPLN

PAPLN
Identifiers
Aliases	PAPLN, papilin, proteoglycan like sulfated glycoprotein, PPN
External IDs	OMIM: 617785; MGI: 2386139; HomoloGene: 71541; GeneCards: PAPLN; OMA:PAPLN - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	73,274,640 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	83,839,156 bp
RNA expression pattern
	Top expressed in
	tibial nerve; ; tendon of biceps brachii; ; decidua; ; trigeminal ganglion; ; spinal ganglia; ; gastric mucosa; ; sural nerve; ; skin of arm; ; left uterine tube; ; lymph node;
	Top expressed in
	molar; ; lip; ; spermatocyte; ; esophagus; ; superior frontal gyrus; ; yolk sac; ; neural layer of retina; ; muscle of thigh; ; primary visual cortex; ; spermatid;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase inhibitor activity; peptidase activity; serine-type endopeptidase inhibitor activity;
Cellular component	extracellular region;
Biological process	negative regulation of peptidase activity; negative regulation of endopeptidase activity; proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	89932
	170721
	ENSG00000100767
	ENSMUSG00000021223
	O95428
	Q9EPX2
	NM_173462; NM_001365906; NM_001365907
	NM_001205343; NM_130887
	NP_775733; NP_001352835; NP_001352836
	NP_001192272; NP_570957
	Wikidata
View/Edit Human	View/Edit Mouse

Papilin is a protein that in humans is encoded by the PAPLN gene.^[5]^[6]^[7] Papilin is an extracellular matrix glycoprotein.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100767 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021223 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: papilin".
^ Kramerova IA, Kawaguchi N, Fessler LI, Nelson RE, Chen Y, Kramerov AA, Kusche-Gullberg M, Kramer JM, Ackley BD, Sieron AL, Prockop DJ, Fessler JH (December 2000). "Papilin in development; a pericellular protein with a homology to the ADAMTS metalloproteinases". Development. 127 (24): 5475–85. doi:10.1242/dev.127.24.5475. PMID 11076767.
^ Apte SS (November 2009). "A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms". J. Biol. Chem. 284 (46): 31493–7. doi:10.1074/jbc.R109.052340. PMC 2797218. PMID 19734141.