OR10T2

OR10T2
Identifiers
Aliases	OR10T2, OR1-3, olfactory receptor family 10 subfamily T member 2
External IDs	HomoloGene: 78313; GeneCards: OR10T2; OMA:OR10T2 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q23.1 Start 158,398,522 bp End 158,399,466 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component membrane integral component of membrane plasma membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 128360 n/a Ensembl ENSG00000186306 n/a UniProt Q8NGX3 n/a RefSeq (mRNA) NM_001004475 n/a RefSeq (protein) NP_001004475 n/a Location (UCSC) Chr 1: 158.4 – 158.4 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Olfactory receptor 10T2 is a protein that in humans is encoded by the OR10T2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

• OR10T2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.