Histochemical tracer

A histochemical tracer is a compound used to reveal the location of cells and track neuronal projections. A neuronal tracer may be retrograde, anterograde, or work in both directions. A retrograde tracer is taken up in the terminal of the neuron and transported to the cell body, whereas an anterograde tracer moves away from the cell body of the neuron.

List

DiI (DiC18(3)) - retrograde and anterograde
Diamidino yellow
Fast blue
Horseradish peroxidase - retrograde
Cholera toxin B^[1]^[2]^[3] - retrograde and anterograde
Pseudorabies virus^[1]
Hydroxystilbamidine - retrograde
Texas Red
Fluorescein isothiocyanate

References

^ ^a ^b Kreier F, Kap YS, Mettenleiter TC, van Heijningen C, van der Vliet J, Kalsbeek A, et al. (March 2006). "Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes". Endocrinology. 147 (3): 1140–1147. doi:10.1210/en.2005-0667. PMID 16339209.
^ Angelucci A, Clascá F, Sur M (March 1996). "Anterograde axonal tracing with the subunit B of cholera toxin: a highly sensitive immunohistochemical protocol for revealing fine axonal morphology in adult and neonatal brains". Journal of Neuroscience Methods. 65 (1): 101–112. doi:10.1016/0165-0270(95)00155-7. PMID 8815303.
^ Coleman JE, Law K, Bear MF (June 2009). "Anatomical origins of ocular dominance in mouse primary visual cortex". Neuroscience. 161 (2): 561–571. doi:10.1016/j.neuroscience.2009.03.045. PMC 2735235. PMID 19327388.

[Kreier_2006-1] Kreier F, Kap YS, Mettenleiter TC, van Heijningen C, van der Vliet J, Kalsbeek A, et al. (March 2006). "Tracing from fat tissue, liver, and pancreas: a neuroanatomical framework for the role of the brain in type 2 diabetes". Endocrinology. 147 (3): 1140–1147. doi:10.1210/en.2005-0667. PMID 16339209.

[2] Angelucci A, Clascá F, Sur M (March 1996). "Anterograde axonal tracing with the subunit B of cholera toxin: a highly sensitive immunohistochemical protocol for revealing fine axonal morphology in adult and neonatal brains". Journal of Neuroscience Methods. 65 (1): 101–112. doi:10.1016/0165-0270(95)00155-7. PMID 8815303.

[3] Coleman JE, Law K, Bear MF (June 2009). "Anatomical origins of ocular dominance in mouse primary visual cortex". Neuroscience. 161 (2): 561–571. doi:10.1016/j.neuroscience.2009.03.045. PMC 2735235. PMID 19327388.

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