Moxastine

Moxastine
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	none;
Identifiers
	IUPAC name 2-[1,1-di(phenyl)ethoxy]-N,N-dimethylethanamine;
CAS Number	3572-74-5 ;
PubChem CID	19142;
ChemSpider	18062 ;
UNII	ZSJ254W6SF;
CompTox Dashboard (EPA)	DTXSID60189244 ;
ECHA InfoCard	100.020.626
Chemical and physical data
Formula	C18H23NO
Molar mass	269.388 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN(C)C;
	InChI InChI=1S/C18H23NO/c1-18(20-15-14-19(2)3,16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-13H,14-15H2,1-3H3 ; Key:BBIMHFSPNXQFAH-UHFFFAOYSA-N ;
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Moxastine (also known as mephenhydramine) is an antihistamine and anticholinergic.^[1]

It was developed in Czechoslovakia^[2] and sold in hydrochloride form as an antihistamine (Alfadryl).

It is, with 8-chlorotheophylline, a component of cocrystal/salt moxastine teoclate (mephenhydrinate) used as antiemetic (Theadryl; Kinedryl (with caffeine)).

References

^ Saxena AK, Saxena M (1992). "Developments in antihistamines (H1)". In Jucker E (ed.). Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques. pp. 35–125. doi:10.1007/978-3-0348-7144-0_3. ISBN 978-3-0348-7146-4.
^ Wardell WM (1978). Controlling the Use of Therapeutic Drugs An International Comparison. Washington, D.C: American Enterprise Institute for Public Policy Research. p. 242. ISBN 978-0-8447-3278-7.

References

See also