Major facilitator superfamily domain-containing protein 9

MFSD9
Identifiers
Aliases	MFSD9, major facilitator superfamily domain containing 9
External IDs	MGI: 2443548; HomoloGene: 13100; GeneCards: MFSD9; OMA:MFSD9 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	102,736,888 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	40,829,847 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; mucosa of transverse colon; ; body of pancreas; ; rectum; ; paraflocculus of cerebellum; ; jejunal mucosa; ; right lobe of liver; ; bone marrow cells; ; duodenum; ; endothelial cell;
	Top expressed in
	secondary oocyte; ; jejunum; ; primary oocyte; ; proximal tubule; ; lumbar spinal ganglion; ; right kidney; ; prostate; ; ileum; ; human kidney; ; large intestine;
	More reference expression data
	n/a
Gene ontology
Molecular function	transporter activity;
Cellular component	membrane; integral component of membrane;
Biological process	transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	84804
	211798
	ENSG00000135953
	ENSMUSG00000041945
	Q8NBP5
	Q8C0T7
	NM_032718; NM_001322080; NM_001322081
	NM_172499
	NP_001309009; NP_001309010; NP_116107
	NP_766087
	Wikidata
View/Edit Human	View/Edit Mouse

Major facilitator superfamily domain-containing protein 9 is a protein that in humans is encoded by the MFSD9 gene. It is a potential solute carrier, and called atypical solute carrier^[5] since it is not named according to the SLC nomenclature.^[6] It is expressed both in central and peripheral organs.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000135953 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041945 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.
^ Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.
^ Perland E, Hellsten SV, Schweizer N, Arapi V, Rezayee F, Bushra M, Fredriksson R (2017). "Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice". PLOS ONE. 12 (10): e0186325. Bibcode:2017PLoSO..1286325P. doi:10.1371/journal.pone.0186325. PMC 5648162. PMID 29049335.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000135953 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041945 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Perland E, Bagchi S, Klaesson A, Fredriksson R (September 2017). "Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression". Open Biology. 7 (9): 170142. doi:10.1098/rsob.170142. PMC 5627054. PMID 28878041.

[6] Perland E, Fredriksson R (March 2017). "Classification Systems of Secondary Active Transporters". Trends in Pharmacological Sciences. 38 (3): 305–315. doi:10.1016/j.tips.2016.11.008. PMID 27939446.

[7] Perland E, Hellsten SV, Schweizer N, Arapi V, Rezayee F, Bushra M, Fredriksson R (2017). "Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice". PLOS ONE. 12 (10): e0186325. Bibcode:2017PLoSO..1286325P. doi:10.1371/journal.pone.0186325. PMC 5648162. PMID 29049335.

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