IGLL5

IGLL5
Identifiers
Aliases	IGLL5, IGL, IGLV, VL-MAR, immunoglobulin lambda like polypeptide 5
External IDs	MGI: 96529; HomoloGene: 131669; GeneCards: IGLL5; OMA:IGLL5 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	22,896,111 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	16,681,849 bp
RNA expression pattern
	Top expressed in
	duodenum; ; rectum; ; bone marrow cells; ; mucosa of transverse colon; ; lymph node; ; spleen; ; tonsil; ; appendix; ; olfactory zone of nasal mucosa; ; salivary gland;
	Top expressed in
	bone marrow; ; granulocyte; ; embryo; ; choroid plexus; ; brown adipose tissue; ; choroid plexus of fourth ventricle; ; Region I of hippocampus proper; ; inferior colliculi; ; secondary oocyte; ; CA3 field;
	More reference expression data
	n/a
Gene ontology
Molecular function	immunoglobulin receptor binding; antigen binding;
Cellular component	extracellular region; blood microparticle; extracellular exosome; external side of plasma membrane; immunoglobulin complex, circulating;
Biological process	B cell receptor signaling pathway; phagocytosis, recognition; positive regulation of B cell activation; phagocytosis, engulfment; innate immune response; defense response to bacterium; complement activation, classical pathway;
	Sources:Amigo / QuickGO
Orthologs
	100423062
	16136
	ENSG00000254709
	ENSMUSG00000075370
	B9A064
	P20764
	NM_001256296; NM_001178126
	NM_001190325
	NP_001171597; NP_001243225
	NP_001177254
	Wikidata
View/Edit Human	View/Edit Mouse

Immunoglobulin lambda like polypeptide 5 is a protein that in humans is encoded by the IGLL5 gene. ^[5]

Function

This gene encodes one of the immunoglobulin lambda-like polypeptides. It is located within the immunoglobulin lambda locus but it does not require somatic rearrangement for expression. The first exon of this gene is unrelated to immunoglobulin variable genes; the second and third exons are the immunoglobulin lambda joining 1 and the immunoglobulin lambda constant 1 gene segments. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000254709 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000075370 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Immunoglobulin lambda like polypeptide 5". Retrieved 2017-10-23.

Function

References

Further reading