ITIH4

ITIH4
Identifiers
Aliases	ITIH4, GP120, H4P, IHRP, ITI-HC4, ITIHL1, PK-120, PK120, inter-alpha-trypsin inhibitor heavy chain family member 4, inter-alpha-trypsin inhibitor heavy chain 4
External IDs	OMIM: 600564; MGI: 109536; HomoloGene: 1670; GeneCards: ITIH4; OMA:ITIH4 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) Band 3p21.1 Start 52,812,962 bp End 52,830,688 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14 B|14 19.09 cM Start 30,608,433 bp End 30,624,310 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of liver right coronary artery popliteal artery tibial arteries left coronary artery body of pancreas muscle of thigh sperm right adrenal cortex gastrocnemius muscle Top expressed in left lobe of liver ascending aorta aortic valve gallbladder tunica media of zone of aorta right lung lobe carotid body sexually immature organism fetal liver hematopoietic progenitor cell embryo More reference expression data BioGPS n/a
Gene ontology Molecular function peptidase inhibitor activity endopeptidase inhibitor activity protein binding serine-type endopeptidase inhibitor activity Cellular component cytoplasm plasma membrane blood microparticle extracellular exosome platelet dense granule lumen extracellular region collagen-containing extracellular matrix Biological process response to cytokine negative regulation of peptidase activity acute-phase response hyaluronan metabolic process platelet degranulation negative regulation of endopeptidase activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3700 16427 Ensembl ENSG00000055955 ENSMUSG00000021922 UniProt Q14624 A6X935 RefSeq (mRNA) NM_002218 NM_001166449 NM_001159299 NM_001289632 NM_001289633 NM_018746 RefSeq (protein) NP_001159921 NP_002209 NP_001152771 NP_001276561 NP_001276562 NP_061216 Location (UCSC) Chr 3: 52.81 – 52.83 Mb Chr 14: 30.61 – 30.62 Mb PubMed search
Wikidata
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Inter-alpha-trypsin inhibitor heavy chain H4 is a protein that in humans is encoded by the ITIH4 gene.

See also

• Inter-alpha-trypsin inhibitor
• ITIH1
• ITIH2
• ITIH3