IMP4

IMP4
Identifiers
Aliases	IMP4, BXDC4, IMP4 homolog, U3 small nucleolar ribonucleoprotein, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 4
External IDs	OMIM: 612981; MGI: 106572; HomoloGene: 68891; GeneCards: IMP4; OMA:IMP4 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	130,347,967 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	34,488,437 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; gastrocnemius muscle; ; body of stomach; ; right lobe of liver; ; muscle of thigh; ; mucosa of transverse colon; ; left coronary artery; ; prefrontal cortex; ; granulocyte; ; apex of heart;
	Top expressed in
	zygote; ; yolk sac; ; primary oocyte; ; morula; ; morula; ; embryo; ; epiblast; ; embryo; ; right kidney; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; rRNA primary transcript binding; snoRNA binding;
Cellular component	small-subunit processome; nucleolus; nucleus; nucleoplasm; fibrillar center; preribosome; Mpp10 complex;
Biological process	ribosome biogenesis; rRNA processing;
	Sources:Amigo / QuickGO
Orthologs
	92856
	27993
	ENSG00000136718
	ENSMUSG00000026127
	Q96G21
	Q8VHZ7
NM_033416; NM_001320304; NM_001320305; NM_001320306; NM_001320307;
	NM_001320309; NM_001320310; NM_001320311; NM_001371725; NM_001371726; NM_001371728; NM_001371730; NM_001371731; NM_001371732; NM_001371733; NM_001371734
	NM_178601
NP_001307233; NP_001307234; NP_001307235; NP_001307236; NP_001307238;
	NP_001307239; NP_001307240; NP_219484; NP_001358654; NP_001358655; NP_001358657; NP_001358659; NP_001358660; NP_001358661; NP_001358662; NP_001358663
	NP_848716
	Wikidata
View/Edit Human	View/Edit Mouse

U3 small nucleolar ribonucleoprotein protein IMP4 is a protein that in humans is encoded by the IMP4 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136718 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026127 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
^ Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
^ "Entrez Gene: IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)".

Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Granneman S, Gallagher JE, Vogelzangs J, et al. (2003). "The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes". Nucleic Acids Res. 31 (7): 1877–87. doi:10.1093/nar/gkg300. PMC 152815. PMID 12655004.
Leary DJ, Terns MP, Huang S (2004). "Components of U3 snoRNA-containing complexes shuttle between nuclei and the cytoplasm and differentially localize in nucleoli: implications for assembly and function". Mol. Biol. Cell. 15 (1): 281–93. doi:10.1091/mbc.E03-06-0363. PMC 307547. PMID 14565981.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136718 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000026127 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8619474-5] Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

[pmid9110174-6] Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.

[entrez-7] "Entrez Gene: IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)".

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[2]

[3]

[4]

[5]

[6]

[7]

References

Further reading