GPBP1

GPBP1
Identifiers
Aliases	GPBP1, GPBP, SSH6, VASCULIN, GC-rich promoter binding protein 1
External IDs	OMIM: 608412; MGI: 1920524; HomoloGene: 11292; GeneCards: GPBP1; OMA:GPBP1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	57,264,679 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	111,626,645 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; cardiac muscle tissue of right atrium; ; Achilles tendon; ; corpus callosum; ; gonad; ; myocardium of left ventricle; ; mucosa of paranasal sinus; ; epithelium of nasopharynx; ; ganglionic eminence; ; mucosa of ileum;
	Top expressed in
	zygote; ; primary oocyte; ; secondary oocyte; ; blood; ; cumulus cell; ; tail of embryo; ; spermatid; ; medial ganglionic eminence; ; hand; ; vestibular sensory epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; protein binding;
Cellular component	cytoplasm; intracellular membrane-bounded organelle; nucleus; cytosol; plasma membrane;
Biological process	positive regulation of transcription, DNA-templated; regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	65056
	73274
	ENSG00000062194
	ENSMUSG00000032745
	Q86WP2
	Q6NXH3
	NM_001127235; NM_001127236; NM_001203246; NM_022913; NM_001331037
NM_001122963; NM_028487; NM_001361923; NM_001361924; NM_001361925;
	NM_001361926
	NP_001120707; NP_001120708; NP_001190175; NP_001317966; NP_075064
NP_001116435; NP_082763; NP_001348852; NP_001348853; NP_001348854;
	NP_001348855
	Wikidata
View/Edit Human	View/Edit Mouse

Vasculin is a protein that in humans is encoded by the GPBP1 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000062194 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032745 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bijnens AP, Gils A, Jutten B, Faber BC, Heeneman S, Kitslaar PJ, Tordoir JH, de Vries CJ, Kroon AA, Daemen MJ, Cleutjens KB (Oct 2003). "Vasculin, a novel vascular protein differentially expressed in human atherogenesis". Blood. 102 (8): 2803–10. doi:10.1182/blood-2003-01-0306. PMID 12842993.
^ "Entrez Gene: GPBP1 GC-rich promoter binding protein 1".

Szafranski K, Schindler S, Taudien S, et al. (2008). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biol. 8 (8): R154. doi:10.1186/gb-2007-8-8-r154. PMC 2374985. PMID 17672918.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Hsu LC, Liu S, Abedinpour F, et al. (2003). "The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription". Mol. Cell. Biol. 23 (23): 8773–85. doi:10.1128/MCB.23.23.8773-8785.2003. PMC 262660. PMID 14612417.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000062194 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032745 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12842993-5] Bijnens AP, Gils A, Jutten B, Faber BC, Heeneman S, Kitslaar PJ, Tordoir JH, de Vries CJ, Kroon AA, Daemen MJ, Cleutjens KB (Oct 2003). "Vasculin, a novel vascular protein differentially expressed in human atherogenesis". Blood. 102 (8): 2803–10. doi:10.1182/blood-2003-01-0306. PMID 12842993.

[entrez-6] "Entrez Gene: GPBP1 GC-rich promoter binding protein 1".

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References

Further reading