GNPDA1

GNPDA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1NE7
Identifiers
Aliases	GNPDA1, GNP1, GNPDA, GNPI, GPI, HLN, glucosamine-6-phosphate deaminase 1
External IDs	OMIM: 601798; MGI: 1347054; HomoloGene: 38054; GeneCards: GNPDA1; OMA:GNPDA1 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	142,013,041 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	38,472,056 bp
RNA expression pattern
	Top expressed in
	beta cell; ; kidney tubule; ; ventricular zone; ; right adrenal cortex; ; retinal pigment epithelium; ; renal medulla; ; human kidney; ; jejunal mucosa; ; metanephric glomerulus; ; left adrenal gland;
	Top expressed in
	yolk sac; ; blastocyst; ; right kidney; ; granulocyte; ; morula; ; tail of embryo; ; proximal tubule; ; neural layer of retina; ; muscle of thigh; ; primary visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; hydrolase activity; glucosamine-6-phosphate deaminase activity; identical protein binding;
Cellular component	extracellular exosome; cytosol; cytoplasm;
Biological process	N-acetylglucosamine metabolic process; generation of precursor metabolites and energy; single fertilization; glucosamine catabolic process; carbohydrate metabolic process; N-acetylglucosamine catabolic process; UDP-N-acetylglucosamine biosynthetic process; N-acetylneuraminate catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	10007
	26384
	ENSG00000113552
	ENSMUSG00000052102
	P46926
	O88958
	NM_005471
	NM_011937
	NP_005462
	NP_036067
	Wikidata
View/Edit Human	View/Edit Mouse

Glucosamine-6-phosphate isomerase 1 is an enzyme that in humans is encoded by the GNPDA1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113552 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000052102 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Shevchenko V, Hogben M, Ekong R, Parrington J, Lai FA (Oct 1998). "The human glucosamine-6-phosphate deaminase gene: cDNA cloning and expression, genomic organization and chromosomal localization". Gene. 216 (1): 31–8. doi:10.1016/S0378-1119(98)00335-7. PMID 9714720.
^ Wolosker H, Kline D, Bian Y, Blackshaw S, Cameron AM, Fralich TJ, Schnaar RL, Snyder SH (Feb 1998). "Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity". FASEB J. 12 (1): 91–9. doi:10.1096/fasebj.12.1.91. PMID 9438414. S2CID 35092971.
^ "Entrez Gene: GNPDA1 glucosamine-6-phosphate deaminase 1".

External links

GNPDA1 human gene location in the UCSC Genome Browser.
GNPDA1 human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000113552 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000052102 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9714720-5] Shevchenko V, Hogben M, Ekong R, Parrington J, Lai FA (Oct 1998). "The human glucosamine-6-phosphate deaminase gene: cDNA cloning and expression, genomic organization and chromosomal localization". Gene. 216 (1): 31–8. doi:10.1016/S0378-1119(98)00335-7. PMID 9714720.

[pmid9438414-6] Wolosker H, Kline D, Bian Y, Blackshaw S, Cameron AM, Fralich TJ, Schnaar RL, Snyder SH (Feb 1998). "Molecularly cloned mammalian glucosamine-6-phosphate deaminase localizes to transporting epithelium and lacks oscillin activity". FASEB J. 12 (1): 91–9. doi:10.1096/fasebj.12.1.91. PMID 9438414. S2CID 35092971.

[entrez-7] "Entrez Gene: GNPDA1 glucosamine-6-phosphate deaminase 1".

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References

Further reading

External links