GLG1

GLG1
Identifiers
Aliases	GLG1, CFR-1, ESL-1, MG-160, MG160, golgi glycoprotein 1
External IDs	OMIM: 600753; MGI: 104967; HomoloGene: 7533; GeneCards: GLG1; OMA:GLG1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	74,607,144 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	111,985,848 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; renal medulla; ; nipple; ; tibia; ; pylorus; ; cardia; ; external globus pallidus; ; corpus callosum; ; ventral tegmental area; ; spinal ganglia;
	Top expressed in
	efferent ductule; ; calvaria; ; epithelium of lens; ; Rostral migratory stream; ; internal carotid artery; ; ciliary body; ; central gray substance of midbrain; ; lacrimal gland; ; right ventricle; ; stroma of bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	fibroblast growth factor binding; signaling receptor binding;
Cellular component	integral component of membrane; plasma membrane; Golgi apparatus; extracellular exosome; membrane; Golgi membrane; extracellular matrix;
Biological process	bone morphogenesis; negative regulation of protein processing; regulation of chondrocyte differentiation; negative regulation of transforming growth factor beta receptor signaling pathway; leukocyte migration;
	Sources:Amigo / QuickGO
Orthologs
	2734
	20340
	ENSG00000090863
	ENSMUSG00000003316
	Q92896
	Q61543
	NM_001145666; NM_001145667; NM_012201
	NM_009149; NM_001368315
	NP_001139138; NP_001139139; NP_036333
	NP_033175; NP_001355244
	Wikidata
View/Edit Human	View/Edit Mouse

Golgi apparatus protein 1 is a protein that in humans is encoded by the GLG1 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000090863 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003316 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mourelatos Z, Gonatas JO, Nycum LM, Gonatas NK, Biegel JA (Feb 1996). "Assignment of the GLG1 gene for MGF-160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus, to chromosome 16q22-q23 by fluorescence in situ hybridization". Genomics. 28 (2): 354–5. doi:10.1006/geno.1995.1156. PMID 8530051.
^ Steegmaier M, Levinovitz A, Isenmann S, Borges E, Lenter M, Kocher HP, Kleuser B, Vestweber D (Mar 1995). "The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor". Nature. 373 (6515): 615–20. Bibcode:1995Natur.373..615S. doi:10.1038/373615a0. PMID 7531823. S2CID 1602373.
^ "Entrez Gene: GLG1 golgi apparatus protein 1".

Burrus LW, Zuber ME, Lueddecke BA, Olwin BB (1992). "Identification of a cysteine-rich receptor for fibroblast growth factors". Mol. Cell. Biol. 12 (12): 5600–9. doi:10.1128/MCB.12.12.5600. PMC 360499. PMID 1448090.
Croul S, Mezitis SG, Stieber A, et al. (1990). "Immunocytochemical visualization of the Golgi apparatus in several species, including human, and tissues with an antiserum against MG-160, a sialoglycoprotein of rat Golgi apparatus". J. Histochem. Cytochem. 38 (7): 957–63. doi:10.1177/38.7.2355176. PMID 2355176.
Mourelatos Z, Gonatas JO, Cinato E, Gonatas NK (1997). "Cloning and sequence analysis of the human MG160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus". DNA Cell Biol. 15 (12): 1121–8. doi:10.1089/dna.1996.15.1121. PMID 8985126.
Steegmaier M, Borges E, Berger J, et al. (1997). "The E-selectin-ligand ESL-1 is located in the Golgi as well as on microvilli on the cell surface". J. Cell Sci. 110 (6): 687–94. doi:10.1242/jcs.110.6.687. PMID 9099943.
Olofsson A, Hellman U, Ten Dijke P, et al. (1997). "Latent transforming growth factor-beta complex in Chinese hamster ovary cells contains the multifunctional cysteine-rich fibroblast growth factor receptor, also termed E-selectin-ligand or MG-160". Biochem. J. 324 (Pt 2): 427–34. doi:10.1042/bj3240427. PMC 1218448. PMID 9182700.
Wild MK, Huang MC, Schulze-Horsel U, et al. (2001). "Affinity, kinetics, and thermodynamics of E-selectin binding to E-selectin ligand-1". J. Biol. Chem. 276 (34): 31602–12. doi:10.1074/jbc.M104844200. PMID 11404363.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yamaguchi F, Morrison RS, Gonatas NK, et al. (2003). "Identification of MG-160, a FGF binding medial Golgi sialoglycoprotein, in brain tumors: an index of malignancy in astrocytomas". Int. J. Oncol. 22 (5): 1045–9. doi:10.3892/ijo.22.5.1045. PMID 12684670.
Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519. S2CID 581283.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
Ahn J, Febbraio M, Silverstein RL (2005). "A novel isoform of human Golgi complex-localized glycoprotein-1 (also known as E-selectin ligand-1, MG-160 and cysteine-rich fibroblast growth factor receptor) targets differential subcellular localization". J. Cell Sci. 118 (Pt 8): 1725–31. doi:10.1242/jcs.02310. PMID 15797922.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000090863 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003316 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8530051-5] Mourelatos Z, Gonatas JO, Nycum LM, Gonatas NK, Biegel JA (Feb 1996). "Assignment of the GLG1 gene for MGF-160, a fibroblast growth factor and E-selectin binding membrane sialoglycoprotein of the Golgi apparatus, to chromosome 16q22-q23 by fluorescence in situ hybridization". Genomics. 28 (2): 354–5. doi:10.1006/geno.1995.1156. PMID 8530051.

[pmid7531823-6] Steegmaier M, Levinovitz A, Isenmann S, Borges E, Lenter M, Kocher HP, Kleuser B, Vestweber D (Mar 1995). "The E-selectin-ligand ESL-1 is a variant of a receptor for fibroblast growth factor". Nature. 373 (6515): 615–20. Bibcode:1995Natur.373..615S. doi:10.1038/373615a0. PMID 7531823. S2CID 1602373.

[entrez-7] "Entrez Gene: GLG1 golgi apparatus protein 1".

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References

Further reading