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Protein-coding gene in the species Homo sapiens
GFPT1 Identifiers Aliases GFPT1 , CMSTA1, GFA, GFAT, GFAT 1, GFAT1, GFAT1m, GFPT, GFPT1L, MSLG, CMS12, glutamine--fructose-6-phosphate transaminase 1External IDs OMIM : 138292 ; MGI : 95698 ; HomoloGene : 68220 ; GeneCards : GFPT1 ; OMA :GFPT1 - orthologs Wikidata
Glucosamine—fructose-6-phosphate aminotransferase isomerizing 1 is an enzyme that in humans is encoded by the GFPT1 gene .[ 5] [ 6]
Glutamine -fructose -6-phosphate transaminase 1 is the first and rate-limiting enzyme of the hexosamine pathway. GFAT controls the flux of glucose into the hexosamine pathway and catalyzes the formation of glucosamine 6-phosphate.[ 6]
^ a b c GRCh38: Ensembl release 89: ENSG00000198380 – Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029992 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ McKnight GL, Mudri SL, Mathewes SL, Traxinger RR, Marshall S, Sheppard PO, O'Hara PJ (Jan 1993). "Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase" . J Biol Chem . 267 (35): 25208–12. doi :10.1016/S0021-9258(19)74026-5 . PMID 1460020 .
^ a b "Entrez Gene: GFPT1 glutamine-fructose-6-phosphate transaminase 1" .
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