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Protein-coding gene in the species Homo sapiens
Polypeptide N-acetylgalactosaminyltransferase 3 is an enzyme that in humans is encoded by the GALNT3 gene .[ 5] [ 6] [ 7]
This gene encodes UDP-GalNAc transferase 3, a member of the polypeptide GalNAc transferase (GalNAc-T) family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O -linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O -glycosylationhomologous to other family members; however, the enzymes have different substrate specificities.[ 7]
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