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GABRR1

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GABRR1
Identifiers
AliasesGABRR1, gamma-aminobutyric acid type A receptor rho1 subunit, gamma-aminobutyric acid type A receptor subunit rho1
External IDsOMIM: 137161; MGI: 95625; HomoloGene: 20470; GeneCards: GABRR1; OMA:GABRR1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256703
NM_001256704
NM_001267582
NM_002042

NM_008075

RefSeq (protein)

NP_001243632
NP_001243633
NP_001254511
NP_002033

NP_032101

Location (UCSC)Chr 6: 89.18 – 89.23 MbChr 4: 33.13 – 33.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gamma-aminobutyric acid receptor subunit rho-1 is a protein that in humans is encoded by the GABRR1 gene.[5][6][7]

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family.[7]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146276Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028280Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Cutting GR, Lu L, O'Hara BF, Kasch LM, Montrose-Rafizadeh C, Donovan DM, Shimada S, Antonarakis SE, Guggino WB, Uhl GR, et al. (May 1991). "Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina". Proc Natl Acad Sci U S A. 88 (7): 2673–2677. Bibcode:1991PNAS...88.2673C. doi:10.1073/pnas.88.7.2673. PMC 51300. PMID 1849271.
  6. ^ Cutting GR, Curristin S, Zoghbi H, O'Hara B, Seldin MF, Uhl GR (May 1992). "Identification of a putative gamma-aminobutyric acid (GABA) receptor subunit rho2 cDNA and colocalization of the genes encoding rho2 (GABRR2) and rho1 (GABRR1) to human chromosome 6q14-q21 and mouse chromosome 4". Genomics. 12 (4): 801–806. doi:10.1016/0888-7543(92)90312-G. PMID 1315307.
  7. ^ a b "Entrez Gene: GABRR1 gamma-aminobutyric acid (GABA) receptor, rho 1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.