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English: Tradeoffs between experimental questions and complexity of microbiome systems.
Each microbiome system is suited to address different types of questions based on the culturability of microbes, genetic tractability of microbes and host (where relevant), ability to maintain system in laboratory setting, and ability to make host/environment germfree. Three different systems are shown in this figure as examples. (A) Pairwise interactions between B. subtilis and Streptomyces spp. are well-suited for characterizing the functions of secondary metabolites in microbial interactions. (B) The symbiosis between bobtail squid and A. fischeri is fundamental to understanding host and microbial factors that influence colonization. (C) The use of gnotobiotic mice is crucial for making links between host diet and the effects on specific microbial taxa in a community
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[1]

doi:10.1128/mSystems.00175-19
Author Marc G. Chevrette, Jennifer R. Bratburd, Cameron R. Currie and Reed M. Stubbendieck. Specific original image credit from the Noun Project: Fertile Soil by Ben Davis; Droplet by Focus; Mouse by Iconic; Cheese Wheel by Anniken & Andreas; Bacteria by Arthur Shlain; Squid by Artem Kovyazin; ant by Yugudesign; leaf by Saeful Muslim

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Tradeoffs between experimental questions and complexity of microbiome systems

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30 July 2019

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Date/TimeThumbnailDimensionsUserComment
current04:39, 28 August 2020Thumbnail for version as of 04:39, 28 August 20201,320 × 470 (174 KB)Epipelagicwiden crop
04:21, 28 August 2020Thumbnail for version as of 04:21, 28 August 20201,280 × 434 (84 KB)EpipelagicUploaded a work by Marc G. Chevrette, Jennifer R. Bratburd, Cameron R. Currie and Reed M. Stubbendieck. Specific original image credit from the [https://thenounproject.com/ Noun Project]: Fertile Soil by Ben Davis; Droplet by Focus; Mouse by Iconic; Cheese Wheel by Anniken & Andreas; Bacteria by Arthur Shlain; Squid by Artem Kovyazin; ant by Yugudesign; leaf by Saeful Muslim from [https://msystems.asm.org/content/4/4/e00175-19.full] {{doi|10.1128/mSystems.00175-19}} with UploadWizard

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