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File:Lathosterol oxidase.svg

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Summary

Description
English: The lathosterol oxidase (EC 1.14.21.6) is an enzyme that catalyzes the chemical reaction
5alpha-cholest-7-en-3beta-ol + NAD(P)H + H+ + O2 cholesta-5,7-dien-3beta-ol + NAD(P)+ + 2 H2O
 
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References

  • DEMPSEY ME, SEATON JD, SCHROEPFER GJ Jr, TROCKMAN RW (1964). "THE INTERMEDIARY ROLE OF DELTA-5,7-CHOLESTADIEN-3-BETA-OL IN CHOLESTEROL BIOSYNTHESIS". J. Biol. Chem. 239: 1381–7. PMID 14189869.
  • Nishino H, Nakaya J, Nishi S, Kurosawa T, Ishibashi T (1997). "Temperature-induced differential kinetic properties between an initial burst and the following steady state in membrane-bound enzymes: studies on lathosterol 5-desaturase". Arch. Biochem. Biophys. 339 (2): 298–304. DOI:10.1006/abbi.1996.9871. PMID 9056262.
  • Taton M, Rahier A (1996). "Plant sterol biosynthesis: identification and characterization of higher plant delta 7-sterol C5(6)-desaturase". Arch. Biochem. Biophys. 325 (2): 279–88. DOI:10.1006/abbi.1996.0035. PMID 8561508.
  • Taton M, Husselstein T, Benveniste P, Rahier A (2000). "Role of highly conserved residues in the reaction catalyzed by recombinant Delta7-sterol-C5(6)-desaturase studied by site-directed mutagenesis". Biochemistry. 39 (4): 701–11. DOI:10.1021/bi991467t. PMID 10651635.
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7 February 2015

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