File:Crystal structures of IRAP in different conformations.png
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Summary
| Description |
English: The four domains are depicted in green, violet, cyan and orange for Domain I, II, III and IV respectively. The zinc atom is shown as a red sphere and the compounds co-crystallized with the enzyme are shown in yellow. A. Crystal structure in the closed conformation (PDB ID 4P8Q), B. Crystal structure in the open conformation (PDB ID 5C97), C. Crystal structure with a linear peptide analogue (PDB ID 4z7i). The enzyme is found in a semi-closed conformation, D. Crystal structure with a macrocyclic peptide inhibitor (PDB ID 6YDX). The enzyme is found in a closed conformation upon binding of the inhibitor. |
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| Source | Own work |
| Author | CAPSTONE-ETN |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 12:17, 20 August 2024 | | 2,042 × 1,364 (2.6 MB) | CAPSTONE-ETN | Uploaded while editing "User:CAPSTONE-ETN/sandbox/IRAP" on wiki.riteme.site |
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