FBRS

FBRS
Identifiers
Aliases	FBRS, FBS, FBS1, fibrosin
External IDs	OMIM: 608601; MGI: 104648; HomoloGene: 79554; GeneCards: FBRS; OMA:FBRS - orthologs
Gene location (Human) Chr. Chromosome 16 (human) Band 16p11.2 Start 30,658,431 bp End 30,670,810 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 F3 Start 127,078,371 bp End 127,090,883 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in left testis right testis right uterine tube anterior pituitary granulocyte right lobe of thyroid gland skin of leg cerebellar vermis left lobe of thyroid gland gastric mucosa Top expressed in granulocyte zygote secondary oocyte thymus spleen primary oocyte lip adrenal gland esophagus bone marrow More reference expression data BioGPS More reference expression data
Gene ontology Molecular function growth factor activity Cellular component extracellular space Biological process positive regulation of fibroblast proliferation regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 64319 14123 Ensembl ENSG00000156860 ENSMUSG00000042423 UniProt Q9HAH7 Q8R089 RefSeq (mRNA) NM_001105079 NM_022452 NM_010183 RefSeq (protein) NP_001098549 NP_034313 Location (UCSC) Chr 16: 30.66 – 30.67 Mb Chr 7: 127.08 – 127.09 Mb PubMed search
Wikidata
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Probable fibrosin-1 long transcript protein is a protein that in humans is encoded by the FBRS gene.

Fibrosin is a lymphokine secreted by activated lymphocytes that induces fibroblast proliferation (Prakash and Robbins, 1998).

Further reading

• Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res. 6 (9): 807–28. doi:10.1101/gr.6.9.807. PMID 8889549.
• Prakash S, Nanji AA, Robbins PW (1999). "Fibrosin: A novel lymphokine in alcohol-induced fibrosis". Exp. Mol. Pathol. 67 (1): 40–9. doi:10.1006/exmp.1999.2274. PMID 10493891.
• Prakash S, Robbins PW (2002). "Fibrosin: a novel lymphokine in wound healing". Exp. Mol. Pathol. 71 (3): 247–55. doi:10.1006/exmp.2001.2402. PMID 11733950.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Prakash S, Paul WE, Robbins PW (2007). "Fibrosin, a novel fibrogenic cytokine, modulates expression of myofibroblasts". Exp. Mol. Pathol. 82 (1): 42–8. doi:10.1016/j.yexmp.2006.06.008. PMID 17083929.