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Formulary (pharmacy)

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A formulary is a list of pharmaceutical drugs, often decided upon by a group of people, for various reasons such as insurance coverage or use at a medical facility.[1] Traditionally, a formulary contained a collection of formulas for the compounding and testing of medication (a resource closer to what would be referred to as a pharmacopoeia today). Today, the main function of a prescription formulary is to specify particular medications that are approved to be prescribed at a particular hospital, in a particular health system, or under a particular health insurance policy. The development of prescription formularies is based on evaluations of efficacy, safety, and cost-effectiveness of drugs.

Depending on the individual formulary, it may also contain additional clinical information, such as side effects, contraindications, and doses.

By the turn of the millennium, 156 countries had national or provincial essential medicines lists and 135 countries had national treatment.

Australia

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In Australia, where there is a public health care system, medications are subsidised under the Pharmaceutical Benefits Scheme (PBS) and medications that are available under the PBS and the indications for which they can be obtained under said scheme can be found in at least two places, the PBS webpage[2] and the Australian Medicines Handbook.[citation needed]

Canada

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The Prescription Drug List is the national formulary that lists all medical ingredients for human and animal use available with a prescription with the exception of those under the Controlled Drugs and Substances Act.[3][4] The Canadian Agency for Drugs and Technologies in Health (CADTH) is the advisory body that evaluates new medical technologies and prescription medication. Based on recommendations the provincial and territorial governments decide whether or not to implement changes to their healthcare system and public drug formularies.[5] Provincial and territorial government provide partial prescription drug coverage and the overall drug payment is a mix of public taxation, private insurance and out-of-pocket expenses.[4][6] Insurance coverage differs regionally, although each public drug coverage plan must meet standards set by the federal government.[6] Regional health authorities are in charge of regulating and providing its residents insurance while the federal government provides insurance for specifically eligible veterans, First Nations, Inuit, Canadian Forces, federal inmates and some refugees.[4][6]

United States

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In the US, where a system of quasi-private healthcare is in place, a formulary is a list of prescription drugs available to enrollees, and a tiered formulary provides financial incentives for patients to select lower-cost drugs. For example, under a 3-tier formulary, the first tier typically includes generic drugs with the lowest cost sharing (e.g., 10% coinsurance), the second includes preferred brand-name drugs with higher cost sharing (e.g., 25%), and the third includes non-preferred brand-name drugs with the highest cost-sharing (e.g., 40%).[7]

When used appropriately, formularies can help manage drug costs imposed on the insurance policy.[7] However, for drugs that are not on formulary, patients must pay a larger percentage of the cost of the drug, sometimes 100%. Formularies vary between drug plans and differ in the breadth of drugs covered and costs of co-pay and premiums. Most formularies cover at least one drug in each drug class, and encourage generic substitution (also known as a preferred drug list).[8] Formularies have shown to cause issues in hospitals when patients are discharged when not aligned with outpatient drug insurance plans.[9]

United Kingdom

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In the UK, the National Health Service (NHS) provides publicly funded universal health care, financed by national health insurance. Here, formularies exist to specify which drugs are available on the NHS. The two main reference sources providing this information are the British National Formulary (BNF) and the Drug Tariff. There is a section in the Drug Tariff, known unofficially as the "Blacklist", detailing medicines which are not to be prescribed under the NHS and must be paid for privately by the patient. Recommendations for additions to the NHS formulary are provided by the National Institute for Health and Care Excellence.[10]

In addition to this, local NHS hospital trusts and Primary Care (General Practitioners) Clinical Commissioning Groups (CCGs), produce their own lists of medicines deemed preferable for prescribing within their locality or organisation; such lists are usually a subset of the more comprehensive BNF. These formularies are not absolutely binding, and physicians may prescribe a non-formulary medicine if they consider it necessary and justifiable. Often, these local formularies are shared between a Primary Care Organisation (PCO) and hospitals within that PCO's jurisdiction, in order to facilitate the procedure of transferring a patient from primary care to secondary care, thus causing fewer "interfacing" issues in the process.

As in the United States, the NHS actively encourages prescribing of generic drugs, in order to save more of the budget allocated to them by the Department of Health.

National formulary

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A national formulary contains a list of medicines that are approved for prescription throughout the country, indicating which products are interchangeable. It includes key information on the composition, description, selection, prescribing, dispensing and administration of medicines. Those drugs considered less suitable for prescribing are clearly identified.

Examples of national formularies are:

See also

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References

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  1. ^ "Definition of formulary by Medical dictionary". TheFreeDictionary.com. Retrieved 2022-11-23.
  2. ^ "Pharmaceutical Benefits Scheme (PBS)".
  3. ^ Canada, Health (2013-05-29). "The Prescription Drug List". www.canada.ca. Retrieved 2022-12-01.
  4. ^ a b c "Alignment Among Public Formularies in Canada – Part 1: General Overview" (PDF). Patented Medicine Prices Review Board. October 2017. ISBN 978-0-660-09799-2.
  5. ^ Allin, Sara; Marchildon, Greg (2020). Merkur, Sherry (ed.). "Canada: Health System Review". Health Systems in Transition. 22 (3). NLM (Medline): 1–194. ISSN 1817-6127. PMID 33527903.
  6. ^ a b c Martin, Danielle; Miller, Ashley P; Quesnel-Vallée, Amélie; Caron, Nadine R; Vissandjée, Bilkis; Marchildon, Gregory P (2018). "Canada's universal health-care system: achieving its potential". The Lancet. 391 (10131): 1718–1735. doi:10.1016/S0140-6736(18)30181-8. PMC 7138369. PMID 29483027.
  7. ^ a b Huskamp HA, Keating NL (2005). "The new medicare drug benefit: formularies and their potential effects on access to medications". J Gen Intern Med. 20 (7): 662–665. doi:10.1007/s11606-005-0115-3. PMC 1403290. PMID 16050866.
  8. ^ New York State Department of Health
  9. ^ Chua, Doson; Chu, Eric; Lo, Angela; Lo, Melissa; Pataky, Fruzina; Tang, Linda; Bains, Ajay (2012). "Effect of Misalignment between Hospital and Provincial Formularies on Medication Discrepancies at Discharge: PPITS (Proton Pump Inhibitor Therapeutic Substitution) Study". The Canadian Journal of Hospital Pharmacy. 65 (2): 98–102. doi:10.4212/cjhp.v65i2.1115. PMC 3329923. PMID 22529401.
  10. ^ Acri née Lybecker, Kristina M. L. (2018-01-08). The Unintended Consequences of National Pharmacare Programs: The Experiences of Australia, New Zealand, and the UK (Report). Fraser Institute. pp. 6–7. The National Institute for Health and Care Excellence (NICE) provides recommendations on whether new branded drugs should be covered by the publicly funded NHS.
  11. ^ "Österreichisches Arzneibuch". BASG (in German). Retrieved 2022-11-22.
  12. ^ "Formularium Nasional Kendalikan Mutu dan Biaya Pengobatan". Indonesian Ministry of Health (in Indonesian). Retrieved 2023-03-02.
  13. ^ "Hrvatska farmakopeja - Hrvatska farmakopeja | Farmakopeja | Lijekovi .: HALMED". .: HALMED (in Croatian). Retrieved 2022-11-22.
  14. ^ Government, PHARMAC | New Zealand. "About the Pharmaceutical Schedule". Pharmac | New Zealand Government. Retrieved 2022-11-23.
  15. ^ a b c FASS – the Swedish Medicines Information Engine Archived 2007-10-23 at the Wayback Machine information booklet from The Swedish Association of the Pharmaceutical Industry (LIF). Updated 2008
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