From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Eukaryotic translation initiation factor 3 subunit B (eIF3b ) is a protein that in humans is encoded by the EIF3B gene .[ 5] [ 6]
EIF3B has been shown to interact with P70-S6 Kinase 1 [ 7] EIF3A .[ 5] [ 8] [ 9] [ 10]
^ a b c GRCh38: Ensembl release 89: ENSG00000106263 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000056076 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ a b Méthot N, Rom E, Olsen H, Sonenberg N (February 1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170" . J. Biol. Chem . 272 (2): 1110–6. doi :10.1074/jbc.272.2.1110 PMID 8995410 . ^ "Entrez Gene: EIF3S9 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa" .^ Holz MK, Ballif BA, Gygi SP, Blenis J (November 2005). "mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events" . Cell . 123 (4): 569–80. doi :10.1016/j.cell.2005.10.024 PMID 16286006 . S2CID 11118504 . ^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (October 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3" . Eur. J. Biochem . 270 (20): 4133–9. doi :10.1046/j.1432-1033.2003.03807.x PMID 14519125 . ^ Harris TE, Chi A, Shabanowitz J, Hunt DF, Rhoads RE, Lawrence JC (April 2006). "mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin" . EMBO J . 25 (8): 1659–68. doi :10.1038/sj.emboj.7601047 . PMC 1440840 PMID 16541103 . ^ Block KL, Vornlocher HP, Hershey JW (November 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3" . J. Biol. Chem . 273 (48): 31901–8. doi :10.1074/jbc.273.48.31901 PMID 9822659 .
Kirken RA, Rui H, Evans GA, Farrar WL (1993). "Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit" . J. Biol. Chem . 268 (30): 22765–70. doi :10.1016/S0021-9258(18)41592-X PMID 7693677 . Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Res . 6 (9): 791–806. doi :10.1101/gr.6.9.791 PMID 8889548 . Asano K, Kinzy TG, Merrick WC, Hershey JW (1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3" . J. Biol. Chem . 272 (2): 1101–9. doi :10.1074/jbc.272.2.1101 PMID 8995409 . Chaudhuri J, Chakrabarti A, Maitra U (1997). "Biochemical characterization of mammalian translation initiation factor 3 (eIF3). Molecular cloning reveals that p110 subunit is the mammalian homologue of Saccharomyces cerevisiae protein Prt1" . J. Biol. Chem . 272 (49): 30975–83. doi :10.1074/jbc.272.49.30975 PMID 9388245 . Block KL, Vornlocher HP, Hershey JW (1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3" . J. Biol. Chem . 273 (48): 31901–8. doi :10.1074/jbc.273.48.31901 PMID 9822659 . Sanger Centre, The; Washington University Genome Sequencing Cente, The (1998). "Toward a complete human genome sequence" . Genome Res . 8 (11): 1097–108. doi :10.1101/gr.8.11.1097 PMID 9847074 . Lin L, Holbro T, Alonso G, Gerosa D, Burger MM (2001). "Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7". J. Cell. Biochem . 80 (4): 483–90. doi :10.1002/1097-4644(20010315)80:4<483::AID-JCB1002>3.0.CO;2-B . PMID 11169732 . S2CID 35848129 . Asano K, Shalev A, Phan L, Nielsen K, Clayton J, Valásek L, Donahue TF, Hinnebusch AG (2001). "Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation" . EMBO J . 20 (9): 2326–37. doi :10.1093/emboj/20.9.2326 . PMC 125443 PMID 11331597 . Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3" . Eur. J. Biochem . 270 (20): 4133–9. doi :10.1046/j.1432-1033.2003.03807.x PMID 14519125 . Fraser CS, Lee JY, Mayeur GL, Bushell M, Doudna JA, Hershey JW (2004). "The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro" . J. Biol. Chem . 279 (10): 8946–56. doi :10.1074/jbc.M312745200 PMID 14688252 . Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5. Bibcode :2004PNAS..10112130B . doi :10.1073/pnas.0404720101 PMC 514446 PMID 15302935 . Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol . 23 (1): 94–101. doi :10.1038/nbt1046 . PMID 15592455 . S2CID 7200157 . Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . ElAntak L, Tzakos AG, Locker N, Lukavsky PJ (2007). "Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit" (PDF) . J. Biol. Chem . 282 (11): 8165–74. doi :10.1074/jbc.M610860200 PMID 17190833 . S2CID 2313046 .
