Draft:NNC2215
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Submission declined on 17 December 2024 by KylieTastic (talk).
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This draft has been resubmitted and is currently awaiting re-review. |  |
NNC2215 is a bioengineered glucose sensitive insulin.
The study was published on Nature on October 16, 2024.[1]
Function
[edit]NNC2215 can sense the glucose concentration. The protein's sensitivity is reduced when low concentration of glucose, thus reducing the risk of hypoglycemia.[2]
See also
[edit]References
[edit]- ^ Hoeg-Jensen, Thomas; Kruse, Thomas; Brand, Christian L.; Sturis, Jeppe; Fledelius, Christian; Nielsen, Peter K.; Nishimura, Erica; Madsen, Alice R.; Lykke, Lennart; Halskov, Kim S.; Koščová, Simona; Kotek, Vladislav; Davis, Anthony P.; Tromans, Robert A.; Tomsett, Michael (16 October 2024). "Glucose-sensitive insulin with attenuation of hypoglycaemia". Nature. 634 (8035): 944–951. Bibcode:2024Natur.634..944H. doi:10.1038/s41586-024-08042-3. ISSN 1476-4687. PMC 11499270. PMID 39415004.
- ^ Kwon, Diana (2024-10-16). "'Smart' insulin prevents diabetic highs — and deadly lows". Nature. doi:10.1038/d41586-024-03357-7. PMID 39414970.
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