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Kenneth Binmoeller

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Kenneth Binmoeller
Photo of Dr. Kenneth Binmoeller
Education
OccupationSurgeon
Known for
  • lumen-apposing metal stent (LAMS)
  • AXIOS
Medical career
FieldGastroenterology
InstitutionsCalifornia Pacific Medical Center
Awards
  • ACG Master Endoscopist of the Year (2013)
  • Da Vinci Award for Endoscopy (2019)
WebsiteKenneth Binmoeller on LinkedIn

Kenneth Frank Binmoeller is a medical doctor and author of multiple scientific contributions[1] and over 300 publications,[2][3] as well as the inventor of the lumen-apposing metal stent (LAMS)[4][5] and AXIOS System.[6][7] These are medical devices used to relieve blockages while creating a direct connection between two bodily structures.[8] He practices in the field of Gastroenterology with a specialty of Advanced Endoscopic Intervention.[9][10] Binmoeller has been published for his innovations in medical devices and training in the field of Endoscopy.[11]

Education and training

[edit]

Binmoeller studied Medicine at the Albert Ludwigs University and graduated in 1983 before he attended medical school at the University of Freiburg in Germany and then at the University of Bern in Switzerland. He completed his Residency in Internal Medicine at the Baylor College of Medicine in Houston, Texas, and followed his residency by working as an attending physician in Honokaa, Hawaii while at Hamakua Medical Center, Honokaa Hospital. Binmoeller then completed a Fellowship in Gastroenterology at the Oregon Health & Science University in Portland.[12][13] Having completed his fellowship, Binmoeller joined the University Hospital (Hôpital Cimiez) at Cimiez in Nice, France.[14]

In 1991, Binmoeller was recruited by and mentored under Dr. Nib Soehendra, known for numerous contributions as a pioneer in the field of therapeutic endoscopy,[15] while at the University Hospital Eppendorf in Hamburg.[16] Binmoeller served as Deputy Director and Senior Consultant in the Department of Endoscopic Surgery.[17]

Career

[edit]

Binmoeller relocated back to the United States after seven years in Hamburg, taking the position of Director of Endoscopy at the University of California at San Diego (UCSD) while holding a joint appointment as Associate Professor of Medicine and Science.[18][17] Binmoeller is certified in gastroenterology and internal medicine by the American Board of Internal Medicine.[19]

He has been certified to practice in the states of:

Binmoeller was affiliated with the California Pacific Medical Center (CPMC) in San Francisco, CA, working as the Medical Director of the Interventional Endoscopy Services (IES).[18] His work in the field of endoscopic procedures is amongst the presentations of the New Frontiers Course, held annually.[23]

Binmoeller has been performing procedures in the field of interventional endoscopy since the 1980s.[24][25][12] Throughout his career as a medical specialist, he has also held university appointments in both Europe and the United States. These include:

In 2001, Binmoeller founded the Interventional Endoscopy Services (IES) at the CPMC, Van Ness Campus and Mission Bernal Campus.[27] This center was founded by Binmoeller, with him as acting Medical Director. The center's focus was on innovating and enabling new procedures in interventional endoscopy while improving existing techniques and technologies.[12][28]

He has collaborated with multiple device manufacturers in an effort to improve existing products. He is also the clinical founder of several medical device start-ups:

  1. Advent - Offered a treatment for GERD (Gastroesophageal Reflux Disease).[29]
  2. Endeau - Founded in September 2012, techniques and devices were developed for underwater endoscopic procedures, or Water-Aided Endoscopy (WAE), aimed at systemizing the way WAE was used in gastroenterology procedures. Binmoeller was the Clinical Director.[30]
  3. Endosphere - Was responsible for multiple patents that enable the psychological treatment of metabolic diseases and obesity. Binmoeller is the inventor of the Satisphere™[31][32] duodenal implant under this startup,[33] a device that has undergone clinical trials.[34][35]
  4. KB Solutions Inc. - Where the novel endoscopic tissue closure device was developed.
  5. Xlumena - Founded in 2004 by Binmoeller (Chief Medical Officer/Board Member)[36] with a portfolio of EUS guided translumenal therapy inventions.[21][7]

Binmoeller is owner of over 100 Endoscopic Technology patents.[37] His first patent was filed in 1998 for an endosonographic guided tissue sampling device.[38] Development and global commercialization was assigned to the Olympus Medical Corporation, which brought the NA-11J-KB Powershot[39] needle to market. He is the inventor of the Lumen-Apposing Metal Stent (LAMS). His work on this was published in the Lumen-Apposing Stents, An Issue of Gastrointestinal Endoscopy Clinics, book.[40][41][25]

International Scholars Program (ISP)

[edit]

ISP has mentored and trained multiple endoscopists from all across the globe[42] and launched a postgraduate program, The International Scholars Program in Advanced Endoscopy, in 2002 in collaboration with Sutter Health and California Pacific Medical Center. Binmoeller supervised a group of endoscopists and nurses, such as Dr. Janek Shah, Dr. Yasser Bhat, and Dr. Chris Hamerski. Its one-year training program reviews a broad spectrum of interventional endoscopic procedures, as well as various techniques like underwater resection of colonic polyps, endoscopic closure of gastrointestinal defects, and endoscopic therapy of subepithelial lesions, among other procedures.[25][43][44] Financial support for scholars is provided by Endovision for ISP.[45]

Non-Profit

[edit]

The Endovision Foundation was Founded by Binmoeller in 2015 in San Francisco, California,[46] and he is the current President and Chief Executive Officer, overseeing management and direction.[47][48]

The AXIOS System

[edit]

Binmoeller invented the AXIOS system for advanced interventional endoscopy. This has two components, the AXIOS Stent and a cautery-enabled access catheter, to provide an Electrocautery Enhanced Delivery System. The system allows an endoscopist to access walled-off necrosis and symptomatic pancreatic pseudocysts by means of a transduodenal or a trans gastric approach to then place the AXIOS stent.[49]

This was the first system of its kind in the United States and is currently the only minimally invasive approach that entirely streamlines the process.[50][51]

Xlumena acquired by Boston Scientific

[edit]

In April 2015, Xlumena was acquired by Boston Scientific[52] when they agreed to pay $62.5 million with an additional $12.5 million for sales-based milestones[53][54] upon FDA clearance of HOT AXIOS,[55] to go alongside the AXIOS Delivery System,[56] which had already received FDA 510(k) clearance[57] as the world’s first stent designed specifically for Endoscopic Ultrasound (EUS) guided transluminal drainage of symptomatic pancreatic pseudocysts.[58][59][60]

Selected honors, awards, and society memberships

[edit]

Honors

[edit]

Awards

[edit]
  • ACG Master Endoscopist of the Year Award (2013)[68]
  • Da Vinci Award for Endoscopy (2019)
  • Gene And Lyn Overholt Endowed Lecture Award (2020)[69]

Memberships

[edit]
  • American Society Gastrointestinal Endoscopy[70]
  • American Gastroenterology Association[71]

Books, publications and articles

[edit]

Books

[edit]
  • Therapeutic endoscopy : color atlas of operative techniques for the gastrointestinal tract. Nib Soehendra. Stuttgart: Thieme. 1998. ISBN 3-13-108261-5. OCLC 37247359.{{cite book}}: CS1 maint: others (link)[72]
  • Lumen-Apposing Stents, An Issue of Gastrointestinal Endoscopy Clinics[73]

Selected publications and articles

[edit]

References

[edit]
  1. ^ "Kenneth F. Binmoeller's research works | California Pacific Medical Center Research Institute, San Francisco and other places". Retrieved 18 November 2023.
  2. ^ "Europe PMC". europepmc.org. Retrieved 7 April 2021.
  3. ^ "Scientific Contributions Kenneth F Binmoeller". ResearchGate.
  4. ^ "ACG MAGAZINE | Vol. 1, No. 1 | Spring 2017 by AmCollegeGastro - Issuu". issuu.com. March 2017. Retrieved 2 December 2022.
  5. ^ "KB_Patents". endovision. Retrieved 7 April 2021.
  6. ^ Patil, Rashmee; Ona, Mel A.; Papafragkakis, Charilaos; Anand, Sury; Duddempudi, Sushil (2016). "Endoscopic ultrasound-guided placement of AXIOS stent for drainage of pancreatic fluid collections". Annals of Gastroenterology. 29 (2): 168–173. doi:10.20524/aog.2016.0008. ISSN 1108-7471. PMC 4805736. PMID 27065729.
  7. ^ a b "AXIOS Stent System Innovator". www.bostonscientific.com. Retrieved 2 December 2022.
  8. ^ "Kenneth F. Binmoeller Inventions, Patents and Patent Applications - Justia Patents Search". patents.justia.com. Retrieved 2 December 2022.
  9. ^ "Dr. Kenneth F. Binmoeller MD". US News.
  10. ^ "Dr. Kenneth F. Binmoeller M.D., Gastroenterologist in San Francisco, CA | Sutter Health". www.sutterhealth.org. Retrieved 2 December 2022.
  11. ^ Bentley, Brooke. "KENNETH F BINMOELLER, M.D., F.A.C.G., F.A.S.G.E." SF Center for Acid Reflux. Retrieved 7 April 2021.
  12. ^ a b c d "AXIOS Stent System Innovator". www.bostonscientific.com. Retrieved 23 October 2022.
  13. ^ "Kenneth Binmoeller". www.bloomberg.com. Retrieved 23 October 2022.
  14. ^ "6th Annual Gastroenterology and Hepatology Symposium Syllabus" (PDF). Department of Medicine | University of California, Irvine | School of Medicine.
  15. ^ Cotton, Peter (March 2015). "Nib Soehendra". 40 Years of Interventional ERCP: Stories from the Pioneers. 2 of 2 (1, 2015): 30 – via mobileportfolio.cookmedical.com/public/14839/14839.
  16. ^ "One of the most innovative and influential endoscopists in ERCP, Dr. Nib Soehendra". Endoscopy. 28 May 2015. Retrieved 2 December 2022.
  17. ^ a b Syllabus medicine.uci.edu
  18. ^ a b Underwater endoscopy：Diving to New Depths jstage.jst.go.jp
  19. ^ "About The Founder". endovision. Retrieved 7 April 2021.
  20. ^ "Kenneth F. Binmoeller, MD - Long Island Live Endoscopic". www.winthropendoscopy.org. Retrieved 7 April 2021.
  21. ^ a b c "Kenneth F. Binmoeller - Founder, President, Chief Medical Officer, Chief Executive Officer, Director of Gastroenterology in San Francisco, California, United States of America | eMedEvents". eMedEvents.com. Retrieved 7 April 2021.
  22. ^ a b "Dr. Kenneth Binmoeller, MD – San Francisco, CA | Gastroenterology on Doximity". Doximity. Retrieved 23 October 2022.
  23. ^ "New Frontiers 2020". endovision. Retrieved 7 April 2021.
  24. ^ "Kenneth F. Binmoeller". Endoscopy On Air. Retrieved 23 October 2022.
  25. ^ a b c "ACG MAGAZINE | Vol. 1, No. 1 | Spring 2017 by AmCollegeGastro - Issuu". issuu.com. March 2017. Retrieved 23 October 2022.
  26. ^ "Kenneth F. Binmoeller, M.D., Founder & Director - Interventional Endoscopy, Endoscopy Specialists". Interventional Endoscopy. 28 April 2019. Retrieved 8 April 2021.
  27. ^ "Dr. Kenneth Binmoeller, MD - Internal Medicine Specialist in San Francisco, CA | Healthgrades". www.healthgrades.com. Retrieved 3 December 2022.
  28. ^ "CPMC Complex Interventional Endoscopy | Sutter Health". www.sutterhealth.org. Retrieved 7 April 2021.
  29. ^ US application 2014330294, Binmoeller, Kenneth F., "Methods and devices for endosonography-guided fundoplexy", published 2014-11-06 , since abandoned.
  30. ^ "Endeau, Inc". Gust. Retrieved 23 October 2022.
  31. ^ "EndoSphere Inc. Receives Patent for Obesity Treatment". BioSpace. Retrieved 2 December 2022.
  32. ^ "New Endoscopically Implantable Device". ResearchGate.
  33. ^ "ISRCTN". www.isrctn.com. Retrieved 2 December 2022.
  34. ^ "ISRCTN - ISRCTN81340421: Investigating the effect and safety of the Satisphere™ insert in overweight patients". www.isrctn.com. Retrieved 21 February 2021.
  35. ^ Kumar, Nitin (25 July 2015). "Endoscopic therapy for weight loss: Gastroplasty, duodenal sleeves, intragastric balloons, and aspiration". World Journal of Gastrointestinal Endoscopy. 7 (9): 847–859. doi:10.4253/wjge.v7.i9.847. ISSN 1948-5190. PMC 4515419. PMID 26240686.
  36. ^ "Bloomberg Profile for Kenneth Binmoeller, Chief Medical Officer, Xlumena Inc". Bloomberg.
  37. ^ "KB_Patents". endovision. Retrieved 21 February 2021.
  38. ^ "Kenneth F. Binmoeller Inventions, Patents and Patent Applications - Justia Patents Search". patents.justia.com. Retrieved 23 October 2022.
  39. ^ "Olympus NA-11J-KB Aspiration Needle" (PDF).
  40. ^ Adler, Douglas G.; Shah, Janak; Nieto, Jose; Binmoeller, Kenneth; Bhat, Yasser; Taylor, Linda Jo; Siddiqui, Ali A. (January 2019). "Placement of lumen-apposing metal stents to drain pseudocysts and walled-off pancreatic necrosis can be safely performed on an outpatient basis: A multicenter study". Endoscopic Ultrasound. 8 (1): 36–42. doi:10.4103/eus.eus_30_17. ISSN 2303-9027. PMC 6400089. PMID 29770780.
  41. ^ Kouanda, Abdul; Binmoeller, Kenneth; Hamerski, Christopher; Nett, Andrew; Bernabe, Jona; Watson, Rabindra (December 2021). "Endoscopic ultrasound-guided gastroenterostomy versus open surgical gastrojejunostomy: clinical outcomes and cost effectiveness analysis". Surgical Endoscopy. 35 (12): 7058–7067. doi:10.1007/s00464-020-08221-z. ISSN 0930-2794. PMID 33479837. S2CID 231669079.
  42. ^ "International Advanced Endoscopy Fellowship Program Graduates | Sutter Health". www.suttermd.com. Retrieved 3 December 2022.
  43. ^ "International Scholar's Program". endovision. Retrieved 8 April 2021.
  44. ^ "International Advanced Endoscopy Fellowship Program Graduates | Sutter Health". www.suttermd.com. Retrieved 2 December 2022.
  45. ^ "International Scholar's Program". endovision. Retrieved 3 December 2022.
  46. ^ "About The Founder". endovision. Retrieved 21 February 2021.
  47. ^ "Endovision Foundation". opencorporates.com. Retrieved 23 October 2022.
  48. ^ "Endovision Officers". endovision. Retrieved 3 December 2022.
  49. ^ Patil, R.; Ona, M. A.; Papafragkakis, C.; Anand, S.; Duddempudi, S. (2016). "Endoscopic ultrasound-guided placement of AXIOS stent for drainage of pancreatic fluid collections - PMC". Annals of Gastroenterology. 29 (2): 168–173. doi:10.20524/aog.2016.0008. PMC 4805736. PMID 27065729.
  50. ^ "AXIOS Stent System Innovator". www.bostonscientific.com. Retrieved 8 April 2021.
  51. ^ "AN INTERVIEW WITH Kenneth Binmoeller, M.D., Director of Interventional Endoscopy Services at California Pacific Medical Center in San Francisco" (PDF). Access: A Boston Scientific Publication (2): 4–5.
  52. ^ "Boston Scientific Boosting Endoscopy Tech with Xlumena Buy". mddionline.com. 2 April 2015. Retrieved 2 August 2022.
  53. ^ Perriello, Brad (1 April 2015). "Boston Scientific ponies up $63m for Xlumena". MassDevice. Retrieved 2 August 2022.
  54. ^ "Boston Scientific to buy California-based medical device firm Xlumena for $75 mn". www.pharmabiz.com. Retrieved 2 August 2022.
  55. ^ Cai, Qiang (2018). "EUS-guided drainage of pancreatic fluid collection with a Hot AXIOS stent in a patient with pancreatitis following distal pancreatectomy (with video)". Endoscopic Ultrasound. 7 (5): 347–348. doi:10.4103/eus.eus_55_17. PMC 6199910. PMID 29848832.
  56. ^ "Boston Scientific Adds More Non-Vascular Stents To MedSurg Business With MI Tech Acquisition". Medtech Insight. 15 June 2022. Retrieved 18 November 2023.
  57. ^ "Xlumena's Axios pancreatic stent's FDA approval". Today's Medical Developments. Retrieved 2 August 2022.
  58. ^ Corporation, Boston Scientific. "Boston Scientific Agrees to Acquire Xlumena". www.prnewswire.com (Press release). Retrieved 2 August 2022.
  59. ^ "Boston Scientific 2018 Annual Report" (PDF). p. 4.
  60. ^ "11. Boston Scientific : Top Global Medical Device Companies in 2017 | Medical Product Outsourcing". www.mpo-mag.com. Retrieved 2 August 2022.
  61. ^ "Dr. Kenneth Binmoeller, MD – San Francisco, CA | Gastroenterology on Doximity". Doximity. Retrieved 8 April 2021.
  62. ^ "UpToDate". www.uptodate.com. Retrieved 23 October 2022.
  63. ^ @asgeendoscopy (20 May 2020). "Congratulations to Nicholas J. Shaheen, MD, MPH, FASGE and Kenneth F. Binmoeller, MD, FASGE!" (Tweet) – via Twitter.
  64. ^ Bentley, Brooke. "Kenneth F Binmoeller, M.D., F.A.C.G., F.A.S.G.E." SF Center for Acid Reflux. Retrieved 8 April 2021.
  65. ^ "Live Webinar: January 20, 2021 New Treatments and Techniques for Managing Patients with Walled Off Pancreatic Necrosis". EndoscopyNow. Retrieved 23 October 2022.
  66. ^ "Dr. Kenneth F. Binmoeller MD Overview". U.S. News & World Report.
  67. ^ "Lecture Series". endovision. Retrieved 8 April 2021.
  68. ^ "Science X Network :: Phys.org, Medical Xpress, Tech Xplore". sciencex.com. Retrieved 23 October 2022.
  69. ^ "Grant and Award Recipients". asge.org. Retrieved 8 April 2021.
  70. ^ "MASGE Members". asge.org. Retrieved 15 December 2022.
  71. ^ Doctorhelps. "Dr. Binmoeller, Internal Medicine, San Francisco, CA". DoctorHelps. Retrieved 15 December 2022.
  72. ^ Reviews of Therapeutic endoscopy : color atlas of operative techniques for the gastrointestinal tract. Nib Soehendra. Stuttgart: Thieme. 1998. ISBN 3-13-108261-5. OCLC 37247359.{{cite book}}: CS1 maint: others (link):
  73. ^ Lumen-Apposing Stents, An Issue of Gastrointestinal Endoscopy Clinics. 1st Edition: Elsevier. 2018. ISBN 9780323583060.{{cite book}}: CS1 maint: location (link)
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