Crack cocaine: Difference between revisions
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[[Image:crack street dosage.jpg|thumb|right|A pile of crack cocaine ‘rocks’.]] |
[[Image:crack street dosage.jpg|thumb|right|A pile of crack cocaine ‘rocks’.]] |
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'''Crack cocaine''' is a highly |
'''Crack cocaine''' is a highly fun form of [[cocaine]] that is popular for its intense [[psychoactive drug|high]]. It is a [[freebase (chemistry)|freebase]] form of the drug that is made using baking soda ([[sodium bicarbonate]]) in a process to convert cocaine hydrochloride (powder cocaine) into freebase cocaine ([[methylbenzoylecgonine]]). |
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== Chemistry == |
== Chemistry == |
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Crack [[cocaine]], often nicknamed "''crack''" due to the sound that is made when smoking it, is believed to have been created and made popular during the [[1980s]]. Because of the dangers for |
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manufacturers of using [[ether]] to produce pure [[Cocaine#Freebase|freebase]] cocaine, producers began to omit the step of removing the freebase [[precipitate]] from the [[ammonia]] mixture. Typically, filtration processes are also omitted. The end result is that the cut, in addition to the ammonium salt (NH<sub><small>4</small></sub>Cl), remains in the freebase cocaine after the mixture has evaporated. The “rock” that is thus formed also contains a small amount of water. |
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[[Image:crackspoon.jpg|thumb|right|A spoon with a mixture of [[baking soda]], cocaine and a small amount of water, when heated from below, small crack cocaine ‘rocks’ will begin to form in the mixture.]] |
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[[Sodium bicarbonate|Baking soda]] is now most often used as a base rather than ammonia for reasons of lowered odor and toxicity; however, any [[weak base]] can be used to make crack cocaine. When commonly "cooked" the ratio is 3:4 parts cocaine per bicarbonate. This acts as a filler which extends the overall profitability of illicit sales. Crack cocaine may be reprocessed in small quantities with water (users refer to the resultant product as "cookback"). This removes the residual bicarbonate, and any [[adulterant]]s or cuts that have been used in the previous handling of the cocaine and leaves a relatively pure, anhydrous cocaine base. The net reaction when using sodium bicarbonate (NaHCO<sub><small>3</small></sub>, common baking soda) is: |
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<div align="center" style="line-height: 2em;">Coc-H<sup><small>+</small></sup>Cl<sup><small>–</small></sup> + NaHCO<sub><small>3</small></sub> → Coc + H<sub><small>2</small></sub>O + CO<sub><small>2</small></sub> + NaCl</div> |
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Crack cocaine usually contains 40% cocaine or less, depending on the degree to which it has been bulked out with other substances. The other 60%-90% can be made up of almost any available substance the chemists and/or dealers have chosen to use. For reasons of salability, the person reducing the purity will obviously prefer to do so with a substance that does not excessively alter the color or odor, and a bulked batch will commonly contain some level of acetone and bicarbonate. The health effects of these are generally mild compared to the health effects of the drug, but a number of highly toxic substances may also be used when available, with serious consequences resulting from consumption. |
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The term "crack" is also used to refer to the water insoluble free base that results from the process of users heating cocaine hydrochloride with dissolved sodium bicarbonate and water. The bicarbonate breaks down into carbon dioxide and sodium carbonate, which then reacts with the hydrochloride from the cocaine molecule,leaving cocaine as a free base and sodium chloride as a byproduct, as in the above reaction. Because the oily free base is not soluble in water, it floats to the top of the liquid and is scraped off for use. The main difference is that it is prepared by the end user, and is less likely to contain intact bicarbonate, being therefore more pure. Because "crack" is a free [[alkaloid]] base, as opposed to a salt (like cocaine hydrochloride or cocaine sulfate) it combusts less in the process of "smoking" and therefore is more potent per unit of substance consumed. Because it is more able to be vaporized, less combusts, and so the term "smoking crack" actually refers to a combination of both vaporization and combustion, whereas with most other smoked substances are "smoked" through a process where combustion constitutes a large portion of the total reaction. Impurities that will be found when crack is produced this way include trace contaminants from the initial reaction (sodium bicarbonate, sodium carbonate) and any other alkaloids that have been used to cut the initial cocaine hydrochloride and can be reduced to their free base by sodium carbonate, or are more soluble in the free base cocaine than in the left-over salt water. Other cutting agents may be more or less soluble in the free base cocaine (crack) and may therefore be either removed from the product of co-purified as contaminants in it. Because the sodium bicarbonate, and sodium carbonate are thought to have little health impact, the result is probably very close to the same as the smoking of crack when prepared with sodium bicarbonate and carbonate left in the mixture. |
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== Psychological effects == |
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Cocaine is a substance that affects the brain chemistry of the user. Its main effect is to release a large amount of [[dopamine]], a brain chemical inducing feelings of [[euphoria (emotion)|euphoria]]. In addition, smoking freebase cocaine releases [[methylecgonidine]] into one's body, something which insufflating or injecting powder cocaine does not do. Methylecgonidine is a methylated form of cocaine in much the same way that [[methamphetamine]] is a methylated form of [[amphetamine]]. The high usually lasts around 15 minutes, after which time dopamine levels in the brain plummet, leaving the user feeling [[depression (mood)|depressed]] and low. A typical response among users is to have another hit of the drug; however, the levels of dopamine in the brain take a long time to replenish themselves, and each hit taken in rapid succession leads to increasingly less intense highs. It is the intense desire to recapture the initial high that is so addictive for many users. |
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Dopamine is used in the formation of [[neural networks]], or ways that people think. If someone does something correctly, the brain releases a small amount of dopamine to reward and encourage similar behaviors - positive reinforcement, in a sense. Crack use leads to the formation of new neural networks that are formed by large amounts of dopamine, which also contributes to the addictive nature of the drug. When users think about crack, the new neural pathways that crack has formed invoke positive emotions, as crack becomes more and more associated with intense euphoria. The increasing exposure to the drug decreases the amount of dopamine that the brain naturally releases, which can permanently affect the neural networks. |
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== Health issues == |
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When large amounts of dopamine are released by crack consumption, it becomes easier for the brain to generate motivation for other activities. The activity also releases a large amount of adrenaline into the body, which tends to increase heart rate and blood pressure, leading to long-term cardiovascular problems. It is suggested by research that smoking crack or freebase cocaine has additional health issues beyond other methods of taking cocaine. Many of these issues relate specifically to the release of methylecgonidine, and the specific effect of methylecgonidine on the heart,<ref>{{cite journal |author=Scheidweiler KB, Plessinger MA, Shojaie J, Wood RW, Kwong TC |title=Pharmacokinetics and pharmacodynamics of methylecgonidine, a crack cocaine pyrolyzate |journal=[[J. Pharmacol. Exp. Ther.]] |volume=307 |issue=3 |pages=1179–87 |year=2003 |pmid=14561847 |doi=10.1124/jpet.103.055434 |url=http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=14561847 |accessdate=2008-02-24}}</ref> lungs,<ref>{{cite journal |author=Yang Y, Ke Q, Cai J, Xiao YF, Morgan JP |title=Evidence for cocaine and methylecgonidine stimulation of M(2) muscarinic receptors in cultured human embryonic lung cells |journal=[[Br. J. Pharmacol.]] |volume=132 |issue=2 |pages=451–60 |year=2001 |pmid=11159694 |doi=10.1038/sj.bjp.0703819 |url=http://dx.doi.org/10.1038/sj.bjp.0703819 |accessdate=2008-02-24}}</ref> and liver.<ref>{{cite journal |author=Fandiño AS, Toennes SW, Kauert GF |title=Studies on hydrolytic and oxidative metabolic pathways of anhydroecgonine methyl ester (methylecgonidine) using microsomal preparations from rat organs |journal=[[Chem. Res. Toxicol.]] |volume=15 |issue=12 |pages=1543–8 |year=2002 |pmid=12482236 |doi= |url=http://dx.doi.org/10.1021/tx0255828 |accessdate=2008-02-24}}</ref> |
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As noted previously, virtually any substance may have been added in order to expand the volume of a batch. Occasionally, highly toxic substances are used, with an indefinite range of corresponding short- and long-term health risks. |
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The task of introducing of the drug into the body further presents a series of health risks. Crack cannot be snorted like regular cocaine, so smoking is the most common consumption method. Crack has a melting point of around {{nowrap|90 °C}} {{nowrap|(194 °F)}}, and the smoke does not remain potent for long. Therefore, crack pipes are generally very short, to minimise the time between evaporating and losing strength. This often causes cracked and blistered lips, colloquially "crack lip", from having a very hot pipe pressed against the lips. The use of "convenience store crack pipes" - glass tubes which originally contained small artificial roses - may also create this condition. These pipes are not durable, but will quickly develop breaks; users will typically continue to use the pipe until it is only about 1/3 of its original length. |
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== Legal status == |
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Crack cocaine is illegal in most parts of the world {{Fact|date=November 2007}}. In the [[United States]] it is a [[Controlled Substances Act#Schedule I drugs|Schedule I]] drug under the [[Controlled Substances Act]]. In the [[United Kingdom]] it is a Class A drug. In the [[Netherlands]] it is a List 1 drug of the Opium Law. In [[Iran]], the term ''crack'' refers to crack [[heroin]] rather than crack cocaine and is a major problem in healthcare. |
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Law enforcement running drug [[Sting operation|stings]] to catch purchasers of crack cocaine often use [[macadamia nut]]s to simulate the drug.<ref>[http://findarticles.com/p/articles/mi_qn4155/is_20041224/ai_n12573039 "Nuts! Cops use holiday treat in drug sting"], Chicago Sun Times, December 24, 2004. Accessed [[21 November]][[2007]].</ref> When chopped, these nuts resemble crack cocaine in color. |
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There has been some controversy over the disproportionate [[mandatory sentencing|mandatory sentences]] for crack cocaine under U.S. law since 1987. Whereas it is a 5-year minimum sentence for trafficking 500g of powdered cocaine, the same sentence can be imposed for mere possession of 5 grams of crack cocaine, a 100:1 ratio. There is no mandatory minimum sentence for mere possession of powder cocaine. <ref>Sabet, Kevin A. Making it Happen: The Case for Compromise in the Federal Cocaine Law Debate</ref> The [[United States Sentencing Commission]] has recommended that this disparity be rectified and existing sentences reduced. <ref>http://www.ussc.gov/PRESS/rel0407.htm</ref> Some claim that this disparity amounts to [[institutional racism]], as crack cocaine is more common in inner-city black communities, and powder cocaine in white suburban communities. |
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== Crack baby == |
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Crack baby is a [[pejorative]] term for a child born to a mother who used [[crack cocaine]] during her pregnancy. There remains some dispute as to whether cocaine use during pregnancy poses a genuine threat to the [[fetus]]. The official opinion of the [[National Institute on Drug Abuse]] of the United States warns about health risks while cautioning against stereotyping: |
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:Many recall that “crack babies,” or babies born to mothers who used crack cocaine while pregnant, were at one time written off by many as a lost generation. They were predicted to suffer from severe, irreversible damage, including reduced intelligence and social skills. It was later found that this was a gross exaggeration. However, the fact that most of these children appear normal should not be overinterpreted as indicating that there is no cause for concern. Using sophisticated technologies, scientists are now finding that exposure to cocaine during fetal development may lead to subtle, yet significant, later deficits in some children, including deficits in some aspects of cognitive performance, information-processing, and attention to tasks—abilities that are important for success in school.<ref>http://www.drugabuse.gov/ResearchReports/Cocaine/cocaine4.html#maternal</ref> |
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== Claims regarding threats to fetal and infant health == |
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They also warn about the threat of [[breastfeeding]]: "It is likely that cocaine will reach the baby through breast milk." |
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The [[March of Dimes]] advises the following regarding cocaine use during pregnancy: |
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:"Cocaine use during pregnancy can affect a pregnant woman and her unborn baby in many ways. During the early months of pregnancy, it may increase the risk of miscarriage. Later in pregnancy, it can trigger preterm labor (labor that occurs before 37 weeks of pregnancy) or cause the baby to grow poorly. As a result, cocaine-exposed babies are more likely than unexposed babies to be born with low birthweight (less than 5½ pounds). Low-birthweight babies are 20 times more likely to die in their first month of life than normal-weight babies, and face an increased risk of lifelong disabilities such as mental retardation and cerebral palsy. Cocaine-exposed babies also tend to have smaller heads, which generally reflect smaller brains. Some studies suggest that cocaine-exposed babies are at increased risk of birth defects, including urinary-tract defects and, possibly, heart defects. Cocaine also may cause an unborn baby to have a stroke, irreversible brain damage, or a heart attack. |
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== See also == |
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*[[War on Drugs]] |
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*[[Drug Abuse]] |
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*[[Crack Epidemic]] |
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== References == |
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<references/> |
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== External links == |
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*[http://www.frankreport.com/Author/Articles/29June00.html Frank Parlato's interview] with two 19-year old crack dealers |
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* [http://www.emcdda.europa.eu/index.cfm?fuseaction=public.Content&nnodeid=25482&sLanguageiso=EN EMCDDA drugs profiles: Cocaine and crack (2007)] |
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* [http://drugaddictionzone.com/questions-and-answers/why-is-crack-so-hard-to-stop-using (US)Why is crack cocaine so hard to stop using?] |
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* [http://www.motherjones.com/news/feature/1995/07/greider.html Crackpot Ideas] - July/August 1995 issue of ''[[Mother Jones (magazine)|Mother Jones]]''. |
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* [http://advocatesforpregnantwomen.org/articles/crackbabyltr.htm Top Medical Doctors and Scientists Urge Major Media Outlets to Stop Perpetuating "Crack Baby" Myth] - a [[petition]]. |
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* [http://www.mapinc.org/drugnews/v98/n809/a07.html US:The Myth of the 'Crack Baby'] |
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* [http://news.bbc.co.uk/1/hi/programmes/file_on_4/7053214.stm The rising peril of crack cocaine (UK)] |
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* [http://jpet.aspetjournals.org/cgi/content/full/307/3/1179#FIG6 Effects of methylecgonidine on heart rate] |
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{{Wiktionary}} |
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{{stimulants}} |
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[[Category:Addiction]] |
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[[Category:Benzoates]] |
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[[Category:Carboxylate esters]] |
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[[Category:Class A drugs]] |
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[[Category:Cocaine]] |
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[[Category:Dopamine reuptake inhibitors]] |
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[[Category:Local anesthetics]] |
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[[Category:Quechua loanwords]] |
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[[Category:Stimulants]] |
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[[Category:Sympathomimetic amines]] |
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[[cs:Crack (droga)]] |
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[[de:Crack (Droge)]] |
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[[es:Crack (droga)]] |
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[[et:Crack]] |
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[[fa:کراک]] |
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[[fr:Crack (stupéfiant)]] |
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[[hr:Crack]] |
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[[is:Krakk]] |
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[[it:Crack (stupefacente)]] |
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[[lt:Krekas]] |
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[[nl:Crack]] |
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[[pt:Crack]] |
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[[sv:Crack (narkotika)]] |
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[[simple:Crack]] |
Revision as of 18:16, 27 February 2008
This article needs additional citations for verification. (February 2008) |
![](http://upload.wikimedia.org/wikipedia/commons/thumb/0/0b/Crack_street_dosage.jpg/220px-Crack_street_dosage.jpg)
Crack cocaine is a highly fun form of cocaine that is popular for its intense high. It is a freebase form of the drug that is made using baking soda (sodium bicarbonate) in a process to convert cocaine hydrochloride (powder cocaine) into freebase cocaine (methylbenzoylecgonine).
Chemistry
FUNFUNFUN