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CSTL1

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(Redirected from CSTL1 (gene))
CSTL1
Identifiers
AliasesCSTL1, CTES1, RCET11, dJ322G13.4, cystatin like 1
External IDsMGI: 2652834; HomoloGene: 16283; GeneCards: CSTL1; OMA:CSTL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_138283

NM_177655
NM_001362207

RefSeq (protein)

NP_612140

NP_808323
NP_001349136

Location (UCSC)Chr 20: 23.44 – 23.44 MbChr 2: 148.59 – 148.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cystatin-like 1 is a protein that in humans is encoded by the CSTL1 gene.[5]

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125823Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000055177Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: CSTL1 cystatin-like 1".
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Further reading

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