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Prednisolamate

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Prednisolamate
Clinical data
Trade namesEtaproctene (with lidocaine and tetryzoline)
Other namesPrednisolone 21-diethylaminoacetate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-N,N-diethylglycine ester
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2-(diethylamino)acetate
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.024.605 Edit this at Wikidata
Chemical and physical data
FormulaC27H39NO6
Molar mass473.610 g·mol−1
3D model (JSmol)
  • CCN(CC)CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)O
  • InChI=1S/C27H39NO6/c1-5-28(6-2)15-23(32)34-16-22(31)27(33)12-10-20-19-8-7-17-13-18(29)9-11-25(17,3)24(19)21(30)14-26(20,27)4/h9,11,13,19-21,24,30,33H,5-8,10,12,14-16H2,1-4H3/t19-,20-,21-,24+,25-,26-,27-/m0/s1
  • Key:ILZSJEITWDWIRX-FOMYWIRZSA-N

Prednisolamate, also known as prednisolone 21-diethylaminoacetate, is a synthetic corticosteroid.[1][2] It is or was a component of Etaproctene, which contains lidocaine, prednisolamate hydrochloride, and tetryzoline.[3]

References

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  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1012–. ISBN 978-1-4757-2085-3.
  2. ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 871–. ISBN 978-3-88763-075-1.
  3. ^ Martindale W, et al. (Royal Pharmaceutical Society of Great Britain. Dept. of Pharmaceutical Sciences) (1993). The Extra Pharmacopoeia. Pharmaceutical Press. p. 737. ISBN 978-0-85369-300-0.