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Omiloxetine

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Omiloxetine
Clinical data
ATC code
  • None
Identifiers
  • 2-[(3R,4S)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-1-piperidinyl]-1-(4-fluorophenyl)ethanone
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC27H25F2NO4
Molar mass465.497 g·mol−1
3D model (JSmol)
Density1.3±0.1 g/cm3
Melting point228.65 °C (443.57 °F)
Boiling point587.2 °C (1,089.0 °F)
Solubility in water0.0015 mg/mL (20 °C)
  • Fc1ccc(cc1)C(=O)CN3CC[C@H](c2ccc(F)cc2)[C@H](C3)COc4ccc5OCOc5c4
  • InChI=1S/C27H25F2NO4/c28-21-5-1-18(2-6-21)24-11-12-30(15-25(31)19-3-7-22(29)8-4-19)14-20(24)16-32-23-9-10-26-27(13-23)34-17-33-26/h1-10,13,20,24H,11-12,14-17H2/t20-,24-/m1/s1
  • Key:FAHGZANUNVVDFL-HYBUGGRVSA-N

Omiloxetine (omiloextinum, omiloxetino INN)[1] was a selective serotonin reuptake inhibitor drug candidate that underwent preclinical development by the Spanish pharmaceutical company, Ferrer Internacional, until 2005, when it was abandoned.[2][3]

Rafael Foguet also patented Abaperidone.

References

[edit]
  1. ^ "Proposed INN: List 76" (PDF). WHO Drug Information. 10 (4): 212–213. 1996.
  2. ^ Terencio J (2005-12-05). "Omiloxetine - Ferrer licensing offer, worldwide". R & D Focus Drug News. Archived from the original on 2016-03-07. Retrieved 2012-05-19.
  3. ^ De Lecea C (2003-12-08). "Omiloxetine - Ferrer partnering opportunity, worldwide Ferrer preclinical data". R & D Focus Drug News. Archived from the original on 2016-03-07. Retrieved 2012-05-19.