Balofloxacin
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| Formula | C20H24FN3O4 |
| Molar mass | 389.427 g·mol−1 |
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Balofloxacin (INN) is a fluoroquinolone antibiotic. It is sold under the brand name Q-Roxin in Korea, and under various names in India.[1] It is not approved by the FDA for use in the United States.
Pharmacodynamics
[edit]Balofloxacin is a fluoroquinolone that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative bacteria, with enhanced activity against Gram positive bacteria, including MRSA and Streptococcus pneumoniae.[2] It functions by inhibiting the action of DNA-gyrase, preventing bacterial cells from reproducing or repairing themselves, resulting in cellular death.[3]
Side Effects
[edit]Vomiting, headache, dizziness, stomach pain, nausea, diarrhea and decreased liver function are the most common side effects. In rare cases, Balofloxacin can lead to or worsen tendinitis,[3] and muscular damage.[3]
See also
[edit]References
[edit]- ^ Alksne L (February 2003). "Balofloxacin Choongwae". Current Opinion in Investigational Drugs. 4 (2): 224–9. PMID 12669387.
- ^ "NCATS Inxight Drugs — BALOFLOXACIN". drugs.ncats.io. Retrieved 2022-07-28.
- ^ a b c "BALOFLOXACINhome: Uses, Side Effects and Medicines | Apollo Pharmacy". www.apollopharmacy.in. Retrieved 2022-07-28.
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