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Ilepcimide

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(Redirected from C15H17NO3)
Ilepcimide
Clinical data
ATC code
  • none
Identifiers
  • (2E)-3-(2H-1,3-Benzodioxol-5-yl)-1-(piperidin-1-yl)prop-2-en-1-one
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC15H17NO3
Molar mass259.305 g·mol−1
3D model (JSmol)
  • C1CCN(CC1)C(=O)/C=C/C2=CC3=C(C=C2)OCO3
  • InChI=1S/C15H17NO3/c17-15(16-8-2-1-3-9-16)7-5-12-4-6-13-14(10-12)19-11-18-13/h4-7,10H,1-3,8-9,11H2/b7-5+ ☒N
  • Key:BLPUOQGPBJPXRL-FNORWQNLSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ilepcimide, also known as antiepilepserine, is an anticonvulsant.[1] It is a piperidine derivative that was first synthesized by Chinese researchers as an analogue of piperine, the main pungent compound and phytochemical of black pepper (and of other plants in the family Piperaceae).

Ilepcimide has serotonergic activity.[1][2][3]

See also

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References

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  1. ^ a b Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. p. 1116. ISBN 978-0-412-46630-4. Retrieved 30 November 2012.
  2. ^ Liu GQ, Algeri S, Ceci A, Garattini S, Gobbi M, Murai S (December 1984). "Stimulation of serotonin synthesis in rat brain after antiepilepsirine, an antiepileptic piperine derivative". Biochemical Pharmacology. 33 (23): 3883–6. doi:10.1016/0006-2952(84)90055-8. PMID 6210090.
  3. ^ Yan QS, Mishra PK, Burger RL, Bettendorf AF, Jobe PC, Dailey JW (May 1992). "Evidence that carbamazepine and antiepilepsirine may produce a component of their anticonvulsant effects by activating serotonergic neurons in genetically epilepsy-prone rats". The Journal of Pharmacology and Experimental Therapeutics. 261 (2): 652–9. PMID 1374472.