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Methimepip

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Methimepip
Names
IUPAC name
4-(1H-imidazol-4-ylmethyl)-1-methylpiperidine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
MeSH C500075
UNII
  • InChI=1S/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12) ☒N
    Key: KIAVPENCSGKVQP-UHFFFAOYSA-N ☒N
  • InChI=1/C10H17N3/c1-13-4-2-9(3-5-13)6-10-7-11-8-12-10/h7-9H,2-6H2,1H3,(H,11,12)
    Key: KIAVPENCSGKVQP-UHFFFAOYAQ
  • CN1CCC(CC1)CC2=CN=CN2
Properties
C10H17N3
Molar mass 179.262 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Methimepip is a histamine agonist which is highly selective for the H3 subtype. It is the N-methyl derivative of immepip.[1]

References

[edit]
  1. ^ Kitbunnadaj R, Hashimoto T, Poli E, et al. (March 2005). "N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist". Journal of Medicinal Chemistry. 48 (6): 2100–7. doi:10.1021/jm049475h. PMID 15771452.


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