AHCTF1

AHCTF1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4I0O
Identifiers
Aliases	AHCTF1, ELYS, MST108, TMBS62, MSTP108, AT-hook containing transcription factor 1
External IDs	OMIM: 610853; MGI: 1915033; HomoloGene: 9142; GeneCards: AHCTF1; OMA:AHCTF1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q44 Start 246,839,098 bp End 246,931,948 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 H4|1 83.62 cM Start 179,572,459 bp End 179,631,245 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell Achilles tendon secondary oocyte sperm ventricular zone Brodmann area 23 testicle internal globus pallidus left testis middle temporal gyrus Top expressed in tail of embryo spermatocyte spermatid genital tubercle epiblast seminiferous tubule zygote secondary oocyte otic placode otic vesicle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm cytosol nuclear membrane nuclear periphery nuclear matrix nuclear pore nucleoplasm chromosome nuclear pore outer ring chromatin extracellular exosome chromosome, centromeric region nucleus kinetochore nuclear envelope Biological process mRNA transport nuclear pore complex assembly regulation of transcription, DNA-templated cytokinesis cell division protein transport cell cycle sister chromatid cohesion transport regulation of transcription by RNA polymerase II regulation of cytokinesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25909 226747 Ensembl ENSG00000153207 ENSMUSG00000026491 UniProt Q8WYP5 Q8CJF7 RefSeq (mRNA) NM_015446 NM_001323342 NM_001323343 NM_175865 NM_026375 RefSeq (protein) NP_001310271 NP_001310272 NP_056261 NP_080651 Location (UCSC) Chr 1: 246.84 – 246.93 Mb Chr 1: 179.57 – 179.63 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Protein ELYS is a protein that in humans is encoded by the AHCTF1 gene.

See also

• AT-hook

External links

• Human AHCTF1 genome location and AHCTF1 gene details page in the UCSC Genome Browser.

Further reading

• Rasala BA, Orjalo AV, Shen Z, et al. (2007). "ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division". Proc. Natl. Acad. Sci. U.S.A. 103 (47): 17801–6. doi:10.1073/pnas.0608484103. PMC 1635652. PMID 17098863.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.